Results 231 to 240 of about 1,425,533 (307)

MUSICiAn: genome-wide identification of genes involved in DNA repair via control-free mutational spectra analysis. [PDF]

NAR Genom Bioinform
Seale C, Barazas M, van Schendel R, Tijsterman M, Gonçalves JP.   +4 more
europepmc   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, EarlyView.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source

Multi-omics reveals immune features in immune and non-immune cells, an IFN-γ/IFN-α-B2M positive feedback loop, and targeted metabolic therapy in multiple myeloma. [PDF]

Front Immunol
Li C, Liao Y, Xu L, Chen Y.
europepmc   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Strangulation during the night: diagnosis of sleep-associated violence. [PDF]

BMC Psychiatry
Guerreiro C, Chedru F, Schenck CH, Arnulf I.   +3 more
europepmc   +1 more source

Visualizing stability: a sensitivity analysis framework for t-SNE embeddings. [PDF]

Front Bioinform
Zabel S, Hennig P, Nieselt K.
europepmc   +1 more source

Japanese wage curve : a pseudo panel study/ by Shigeki Kano

Japanese wage curve : a pseudo panel study/ by Shigeki Kano
Includes bibliographical ...
openaire  

Unsaturated Phosphorus Electrophiles to Probe Protein Tyrosine Phosphatases

Angewandte Chemie International Edition, EarlyView.
Charged aryl‐ethynyl phosphonamidic and phosphonic acids are introduced as low‐reactivity electrophiles for peptide‐based activity probes that enable selective, target‐specific profiling of protein tyrosine phosphatases. The probes show no off‐target cysteine reactivity and engage only the interacting phosphatase in global proteomic analysis.
Eleftheria Poulou, Max Ruwolt, Christian E. Stieger, Kristin Kemnitz‐Hassanin, Christian P. R. Hackenberger   +4 more
wiley   +1 more source

Towards annual updating of forced warming to date and constrained climate projections. [PDF]

Nat Commun
Ribes A, Tessiot O, Forster PM, Gillett NP, Masson-Delmotte V, Rogelj J, Vautard R, Walsh T.   +7 more
europepmc   +1 more source

B cell subpopulations and their role in the pathogenesis of primary Sjögren's syndrome: insights from single-cell RNA sequencing. [PDF]

Front Immunol
Zhang X, Han Y, Zhang J, Song Y, Zhou Y, Wang J, Tian J, Xin X, Liu B, Fang L, Zhu H.   +10 more
europepmc   +1 more source