Results 91 to 100 of about 142,435 (303)

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

open access: yesAdvanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi   +22 more
wiley   +1 more source

CLARITY at the TREC 2011 microblog track [PDF]

open access: yes, 2011
For the first year of the TREC Microblog Track the CLARITY group concentrated on a number of areas, investigating the underlying term weighting scheme for ranking tweets, incorporating query expansion to introduce new terms into the query, as well as ...
Ferguson, Paul   +6 more
core  

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

Parsimonious Language Models for a Terabyte of Text [PDF]

open access: yes, 2008
The aims of this paper are twofold. Our first aim\ud is to compare results of the earlier Terabyte tracks\ud to the Million Query track. We submitted a number\ud of runs using different document representations\ud (such as full-text, title-fields, or ...
Hiemstra, Djoerd   +3 more
core   +2 more sources

Knowledge-based Query Expansion in Real-Time Microblog Search

open access: yes, 2015
Since the length of microblog texts, such as tweets, is strictly limited to 140 characters, traditional Information Retrieval techniques suffer from the vocabulary mismatch problem severely and cannot yield good performance in the context of ...
Fan, Feifan   +3 more
core   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo   +6 more
wiley   +1 more source

Query dependent pseudo-relevance feedback based on wikipedia [PDF]

open access: yesProceedings of the 32nd international ACM SIGIR conference on Research and development in information retrieval, 2009
Pseudo-relevance feedback (PRF) via query-expansion has been proven to be e®ective in many information retrieval (IR) tasks. In most existing work, the top-ranked documents from an initial search are assumed to be relevant and used for PRF. One problem with this approach is that one or more of the top retrieved documents may be non-relevant, which can ...
Xu, Yang, Jones, Gareth J.F., Wang, Bin
openaire   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

open access: yesAdvanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park   +11 more
wiley   +1 more source

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