Results 171 to 180 of about 25,500,900 (299)

AI‐EXAFS: Physics‐Informed Prediction of EXAFS from Atomic Structure

open access: yesAdvanced Science, EarlyView.
AI‐EXAFS presents a neural network to reproduce EXAFS. Trained on synthetic data and with a careful selection of the settings both for the physical representation of the system and following the experimental heuristic loss functions, the model is capable of reproducing EXAFS spectra for molecules from the tridimensional structure.
Javier Heras‐Domingo   +6 more
wiley   +1 more source

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

open access: yesAdvanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang   +11 more
wiley   +1 more source

Data‐Driven and Physics‐Informed Modeling Perspectives for Soft Manipulators: From SINDy to Hybrid Intelligence

open access: yesAdvanced Science, EarlyView.
This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui   +4 more
wiley   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

open access: yesAdvanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang   +7 more
wiley   +1 more source

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy. [PDF]

open access: yesJ Anat
Shotar E   +30 more
europepmc   +1 more source

Flooding‐Driven Greenhouse Gas Emissions From Global Upland Croplands

open access: yesAdvanced Science, EarlyView.
Temporary flooding of upland croplands releases nitrous oxide, carbon dioxide, and methane. Field measurements combined with a global literature synthesis yield a global estimate of 63.3 teragrams of carbon dioxide equivalent per year for diffusive emissions from flooded upland croplands.
Shuilian Bi   +7 more
wiley   +1 more source

SpaCut: Transcript‐Aware Morphology Fusion for Robust Cell Segmentation in Subcellular Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Subcellular spatial transcriptomics enables high‐resolution mapping of gene expression within tissues, but accurate cell segmentation is essential for assigning transcripts to individual cells. We present SpaCut, a deep learning framework that integrates transcriptomic features with nucleus‐guided morphological information to precisely delineate cell ...
Yongheng Li, Fangfang Zhu, Wenwen Min
wiley   +1 more source

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