Results 181 to 190 of about 25,500,900 (299)

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

open access: yesAdvanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau   +3 more
wiley   +1 more source

STRIDE: A Sequencing Depth Robust Metric for Sparse Chromosome Conformation Capture Data Comparison

open access: yesAdvanced Science, EarlyView.
A mean first passage time (MFPT)‐based representation transforms sparse Hi‐C contact maps into robust topological representations, preserving biologically meaningful chromatin features and facilitating robust analysis of TADs, chromatin loops, differential chromatin contacts, and sparse single‐cell Hi‐C data.
Bingxiang Xu   +4 more
wiley   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu   +5 more
wiley   +1 more source

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

open access: yesAdvanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin   +7 more
wiley   +1 more source

A Case of Pseudo-Richter Transformation Following Zanubrutinib Discontinuation in CLL. [PDF]

open access: yesMediterr J Hematol Infect Dis
Laurenti L   +14 more
europepmc   +1 more source

What Really Drives Agri‐Environment‐Climate Measures' Adoption? Mandatory Requirements, Behavioral Traits, and Structural Factors in the CAP Green Architecture

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT To increase farmer adoption of green practices, the EU Common Agricultural Policy includes both mandatory (conditionality) and voluntary instruments (eco‐schemes–ECS– and more demanding, multi‐annual agri‐environment‐climate measures –AECM–). Building on the experiment of Barreiro‐Hurle et al.
L. Sanchez‐Mata   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy