Results 1 to 10 of about 14,834 (261)

Pseudoknots in a Homopolymer [PDF]

open access: yesPhysical Review E, 2003
After a discussion of the definition and number of pseudoknots, we reconsider the self-attracting homopolymer paying particular attention to the scaling of the number of pseudoknots at different temperature regimes in two and three dimensions.
Kabakcioglu, A., Stella, A. L.
core   +3 more sources

Inverse folding of RNA pseudoknot structures [PDF]

open access: yesAlgorithms for Molecular Biology, 2010
Background RNA exhibits a variety of structural configurations. Here we consider a structure to be tantamount to the noncrossing Watson-Crick and G-U-base pairings (secondary structure) and additional cross-serial base pairs.
Li Linda YM   +2 more
doaj   +5 more sources

Tree decomposition and parameterized algorithms for RNA structure-sequence alignment including tertiary interactions and pseudoknots [PDF]

open access: yes, 2012
We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures.
Barth, Dominique   +3 more
core   +3 more sources

Slip of grip of a molecular motor on a crowded track: Modeling shift of reading frame of ribosome on RNA template

open access: yes, 2016
We develop a stochastic model for the programmed frameshift of ribosomes synthesizing a protein while moving along a mRNA template. Normally the reading frame of a ribosome decodes successive triplets of nucleotides on the mRNA in a step-by-step manner ...
Chowdhury, Debashish   +2 more
core   +1 more source

A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshifting

open access: yesVirology Journal, 2009
Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expression strategy, resulting in ~10 mature proteins.
Atkins John F, Firth Andrew E
doaj   +1 more source

Use of RNA secondary structure for evolutionary relationships : investigating RNase P and RNase MRP : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, New Zealand [PDF]

open access: yes, 1998
Bioinformatics is applied here to examine whether RNA secondary structure data can reflect distant evolutionary relationships. This is important when there is little confidence in sequence data such as when looking at the evolution of RNase MRP (MRP ...
Collins, Lesley Joan
core  

Ab initio RNA folding

open access: yes, 2014
RNA molecules are essential cellular machines performing a wide variety of functions for which a specific three-dimensional structure is required. Over the last several years, experimental determination of RNA structures through X-ray crystallography and
Cragnolini, Tristan   +2 more
core   +1 more source

An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing

open access: yesCell Reports, 2017
Tumor necrosis factor alpha (TNF-α) is expressed promptly during inflammatory responses. Efficient TNF-α mRNA splicing is achieved through a 3′ UTR element that activates RNA-dependent eIF2α protein kinase (PKR).
Lise Sarah Namer   +5 more
doaj   +1 more source

Translocation of structured polynucleotides through nanopores

open access: yes, 2004
We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic barriers for the ...
Akeson M   +20 more
core   +1 more source

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