Results 111 to 120 of about 14,400 (274)
Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.Viral haemorrhagic septicaemia virus (VHSV) immunogenic epitopes were used to design a multi‐epitope vaccine with adjuvant. The vaccine's properties, structure and TLR‐4 interaction were analysed via computational methods. Optimized nucleotide sequences were created for Lactococcus lactis expression.
Ramin Shukripour +3 more
wiley +1 more source
Fatgraph models of RNA structure
Computational and Mathematical Biophysics, 2017 In this review paper we discuss fatgraphs as a conceptual framework for RNA structures. We discuss various notions of coarse-grained RNA structures and relate them to fatgraphs.We motivate and discuss the main intuition behind the fatgraph model and ...
Huang Fenix +2 more
doaj +1 more source
A bacterial riboswitch class for the thiamin precursor HMP-PP employs a terminator-embedded aptamer
eLife, 2019 We recently implemented a bioinformatics pipeline that can uncover novel, but rare, riboswitch candidates as well as other noncoding RNA structures in bacteria.
Ruben M Atilho +4 more
doaj +1 more source
Structure and folding of the Tetrahymena telomerase RNA pseudoknot
Nucleic Acids Research, 2016 Telomerase maintains telomere length at the ends of linear chromosomes using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT).
D. Cash, J. Feigon
semanticscholar +1 more source
Harnessing Noncanonical Proteins for Next‐Generation Drug Discovery and Diagnosis
WIREs Mechanisms of Disease, Volume 17, Issue 3, May/June 2025.Noncanonical proteins: Emerging players in human health and disease. This figure illustrates the discovery, characterization, and functional significance of noncanonical proteins across various biological processes and disease states, highlighting their potential as novel therapeutic targets and biomarkers for personalized medicine approaches ...
Nachiket Rajinikanth +2 more
wiley +1 more source
Psybrackets, Pseudoknots and Singular Knots [PDF]
arXiv, 2020 We introduce algebraic structures known as psybrackets and use them to define invariants of pseudoknots and singular knots and links. Psybrackets are Niebrzydowski tribrackets with additional structure inspired by the Reidemeister moves for pseudoknots and singular knots. Examples and computations are provided.
arxiv
Nucleic Acids Research, 2017 Cricket paralysis virus (CrPV) is a dicistrovirus. Its positive-sense single-stranded RNA genome contains two internal ribosomal entry sites (IRESs). The 5′ untranslated region (5′UTR) IRES5′UTR mediates translation of non-structural proteins encoded by ...
Lauriane Gross +9 more
semanticscholar +1 more source
Structural Biology of RNA and Protein‐RNA Complexes after AlphaFold3
ChemBioChem, Volume 26, Issue 7, April 1, 2025.AlphaFold is a great research accelerator and hypothesis generator for structural biology and beyond. With the release of AlphaFold3, RNA and protein‐RNA complex structure prediction is readily possible. This review assesses the reliability of these predictions.
Janosch Hennig
wiley +1 more source
Nucleic Acids Research, 2018 Telomerase adds telomeric repeats to chromosome ends by processive copying of a template within the telomerase RNA bound to telomerase reverse transcriptase.
A. Deshpande, K. Collins
semanticscholar +1 more source
Psyquandle Coloring Quivers [PDF]
arXiv, 2021 We enhance the psyquandle counting invariant for singular knots and pseudoknots using quivers analogously to quandle coloring quivers. This enables us to extend the in-degree polynomial invariants from quandle coloring quiver theory to the case of singular knots and pseudoknots.
arxiv