Results 121 to 130 of about 14,795 (267)
Virology Journal, 2009 Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expression strategy, resulting in ~10 mature proteins.
Atkins John F, Firth Andrew E
doaj +1 more source
Automatic generation of pseudoknotted RNAs taxonomy
BMC Bioinformatics, 2023 Background The ability to compare RNA secondary structures is important in understanding their biological function and for grouping similar organisms into families by looking at evolutionarily conserved sequences such as 16S rRNA. Most comparison methods
Michela Quadrini +2 more
doaj +1 more source
Dual Graph Partitioning Highlights a Small Group of Pseudoknot-Containing RNA Submotifs
Genes, 2018 RNA molecules are composed of modular architectural units that define their unique structural and functional properties. Characterization of these building blocks can help interpret RNA structure/function relationships.
Swati Jain +3 more
semanticscholar +1 more source
Engineered RNA Devices for In Vivo Targeted Therapeutics via Advanced Delivery Systems
Aggregate, Volume 6, Issue 11, November 2025.Schematic illustration of engineered RNA devices for in vivo targeted therapeutics via advanced delivery systems. ABSTRACT Engineered RNA devices can identify disease‐specific markers and precisely regulate gene expression, which is of great significance to the development of precision medicine.
Wei Luo +6 more
wiley +1 more source
Classifying RNA pseudoknotted structures
Theoretical Computer Science, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Condon, Anne +4 more
openaire +4 more sources
PLoS ONE, 2016 The hepatitis C virus (HCV) internal ribosome entry site (IRES) that directs cap-independent viral translation is a primary target for small interfering RNA (siRNA)-based HCV antiviral therapy. However, identification of potent siRNAs against HCV IRES by
Jae-Su Moon +9 more
semanticscholar +1 more source
The Chemical Record, Volume 25, Issue 10, October 2025.This review explores aptamers as therapeutic oligonucleotides targeting neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, with a focus on G‐quadruplex‐forming sequences. It discusses chemical modifications that enhance aptamer stability and function, alongside the use of clay nanoparticles, such as halloysite nanotubes ...
Valentina Arciuolo +9 more
wiley +1 more source
ASPRAlign: a tool for the alignment of RNA secondary structures with arbitrary pseudoknots [PDF]
, 2020 Michela Quadrini +2 more
openalex +1 more source
Nucleic Acids Research, 2017 Massive all-atom molecular dynamics simulations were conducted across a distributed computing network to study the folding, unfolding, misfolding and conformational plasticity of the high-efficiency frameshifting double mutant of the 26 nt potato leaf ...
Khai K. Q. Nguyen +7 more
semanticscholar +1 more source
Discovery of RNA‐Targeting Small Molecules: Challenges and Future Directions
MedComm, Volume 6, Issue 9, September 2025.This review explores challenges and future directions in discovering RNA‐targeting small molecules, from analyzing RNA structures and computational design to experimental workflows. It discusses mechanistic strategies like splicing modulation and RNA degradation, alongside advanced tools (deep learning, docking, and validation) to accelerate drug ...
Zhengguo Cai +7 more
wiley +1 more source