Results 121 to 130 of about 14,400 (274)
Recent Advances in Biosensors Based on Hybridization Chain Reaction and Silver Nanoclusters
Small Methods, Volume 9, Issue 4, April 22, 2025.This review explores the integration of hybridization chain reaction (HCR) with silver nanoclusters (AgNCs) to form hybrid HCR‐AgNCs biosensors, highlighting advancements in their design, performance, and practical applications. It covers recent innovations, methodological improvements, and the potential of HCR‐AgNCs systems as detectors across various
Zheng Wei Wong, Siu Yee New
wiley +1 more source
Stacks in canonical RNA pseudoknot structures [PDF]
Mathematical Biosciences, 2009 In this paper we study the distribution of stacks in $k$-noncrossing, $ $-canonical RNA pseudoknot structures ($ $-structures). An RNA structure is called $k$-noncrossing if it has no more than $k-1$ mutually crossing arcs and $ $-canonical if each arc is contained in a stack of length at least $ $.
Hillary S. W. Han, Christian M. Reidys
openaire +4 more sources
Isotopy and Homotopy Invariants of Classical and Virtual Pseudoknots [PDF]
arXiv, 2013 Pseudodiagrams are knot or link diagrams where some of the crossing information is missing. Pseudoknots are equivalence classes of pseudodiagrams, where equivalence is generated by a natural set of Reidemeister moves. In this paper, we introduce a Gauss-diagrammatic theory for pseudoknots which gives rise to the notion of a virtual pseudoknot.
arxiv
PLoS ONE, 2016 The hepatitis C virus (HCV) internal ribosome entry site (IRES) that directs cap-independent viral translation is a primary target for small interfering RNA (siRNA)-based HCV antiviral therapy. However, identification of potent siRNAs against HCV IRES by
Jae-Su Moon +9 more
semanticscholar +1 more source
Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders
Cell Proliferation, Volume 58, Issue 4, April 2025.This review outlines the latest research advancements in prime editing technology, delivery strategies, and the challenges that must be addressed to fully realize its therapeutic potential, emphasizing the high potential of prime editing in the remission or cure of genetic diseases. ABSTRACT Genetic diseases have long posed significant challenges, with
Mengyao Li, Yi Lin, Qiang Cheng, Tuo Wei
wiley +1 more source
Potential biological roles of exosomal non‐coding RNAs in breast cancer
The FASEB Journal, Volume 39, Issue 6, 31 March 2025.ncRNAs are enriched in exosomes and play a critical role in regulating cell proliferation, metastasis, drug resistance, and angiogenesis in BC. Consequently, exosomal ncRNAs have emerged as a promising therapeutic targets for BC treatment, given their involvement in multiple processes of cancer progression.
Xiang Li +5 more
wiley +1 more source
Scientific Reports, 2016 Minus-one ribosomal frameshifting is a translational recoding mechanism widely utilized by many RNA viruses to generate accurate ratios of structural and catalytic proteins. An RNA pseudoknot structure located in the overlapping region of the gag and pro
Zhensheng Zhong +8 more
semanticscholar +1 more source
Science-Business eXchange, 2011 In vitro studies identified an RNA-binding ligand that could help treat SARS-associated coronavirus infection.
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Virology Journal, 2009 Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expression strategy, resulting in ~10 mature proteins.
Atkins John F, Firth Andrew E
doaj +1 more source
PLoS Biology, 2015 In eukaryotes, the highly conserved U3 small nucleolar RNA (snoRNA) base-pairs to multiple sites in the pre-ribosomal RNA (pre-rRNA) to promote early cleavage and folding events.
Richa Sardana +9 more
semanticscholar +1 more source