Results 141 to 150 of about 14,400 (274)

RNA structure prediction: progress and perspective

open access: yes, 2014
Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures.
Shi, Ya-Zhou   +3 more
core   +1 more source

Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel.

open access: yesJournal of the American Chemical Society, 2015
Pseudoknots are a fundamental RNA tertiary structure with important roles in regulation of mRNA translation. Molecular force spectroscopic approaches such as optical tweezers can track the pseudoknot's unfolding intermediate states by pulling the RNA ...
Xinyue Zhang   +6 more
semanticscholar   +1 more source

An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing

open access: yesCell Reports, 2017
Tumor necrosis factor alpha (TNF-α) is expressed promptly during inflammatory responses. Efficient TNF-α mRNA splicing is achieved through a 3′ UTR element that activates RNA-dependent eIF2α protein kinase (PKR).
Lise Sarah Namer   +5 more
doaj   +1 more source

Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring

open access: yesAdvanced Science, Volume 12, Issue 2, January 13, 2025.
Bioreceptor‐based wearable electrochemical sensors have opened new avenues for on‐body and continuous molecular detections, enabling personalized and preventive healthcare. This review summarises recent innovations and applications of those wearable biosensing systems in detecting a variety of biochemical markers, such as small molecules, hormones ...
Haowei Duan   +6 more
wiley   +1 more source

An Algorithm for RNA Pseudoknots

open access: yes, 2003
21 pages, 14 ...
Pillsbury, M.   +3 more
openaire   +2 more sources

Ensemble simulations: folding, unfolding and misfolding of a high-efficiency frameshifting RNA pseudoknot

open access: yesNucleic Acids Research, 2017
Massive all-atom molecular dynamics simulations were conducted across a distributed computing network to study the folding, unfolding, misfolding and conformational plasticity of the high-efficiency frameshifting double mutant of the 26 nt potato leaf ...
Khai K. Q. Nguyen   +7 more
semanticscholar   +1 more source

Shapes of topological RNA structures [PDF]

open access: yes, 2014
A topological RNA structure is derived from a diagram and its shape is obtained by collapsing the stacks of the structure into single arcs and by removing any arcs of length one. Shapes contain key topological, information and for fixed topological genus
Christian M. Reidys, Fenix W. D, Huang
core  

On pseudoknot-bordered words and their properties

open access: yesJournal of Computer and System Sciences, 2009
AbstractWe study a generalization of the classical notions of bordered and unbordered words, motivated by biomolecular computing. DNA strands can be viewed as finite strings over the alphabet {A, G, C, T}, and are used in biomolecular computing to encode information.
Shinnosuke Seki, Lila Kari
openaire   +2 more sources

A dynamic programming algorithm for RNA structure prediction including pseudoknots [PDF]

open access: yesarXiv, 1998
We describe a dynamic programming algorithm for predicting optimal RNA secondary structure, including pseudoknots. The algorithm has a worst case complexity of ${\cal O}(N^6)$ in time and ${\cal O}(N^4)$ in storage. The description of the algorithm is complex, which led us to adopt a useful graphical representation (Feynman diagrams) borrowed from ...
arxiv  

Tree decomposition and parameterized algorithms for RNA structure-sequence alignment including tertiary interactions and pseudoknots [PDF]

open access: yes, 2012
We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures.
Barth, Dominique   +3 more
core   +3 more sources

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