Results 101 to 110 of about 863,963 (349)

The transmission of nosocomial pathogens in an intensive care unit: a space–time clustering and structural equation modelling approach [PDF]

open access: yes, 2010
We investigated the incidence of cases of nosocomial pathogens and risk factors in an intensive treatment unit ward to determine if the number of cases is dependent on location of patients and the colonization/infection history of the ward.
A. G. O'DONNELL   +6 more
core   +1 more source

Biocatalytic Construction of a Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Nucleoside Probe: Synthesis and Evaluation of 5‐Methyl‐5,6‐Dihydrothymidine

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Al‐Hilfi et al. present a biocatalytic strategy for synthesizing 5‐methyl‐5,6‐dihydrothymidine (5‐MDHT), a sensitive MRI contrast agent. The study demonstrates that recombinant enzyme catalysis offers an efficient, sustainable, and eco‐friendly alternative to traditional chemical synthesis for producing clinically relevant imaging probes.
Aimen Al‐Hilfi   +8 more
wiley   +1 more source

Presence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]

open access: yes, 2016
Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...
Biernaskie, Jay   +3 more
core   +2 more sources

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid   +8 more
wiley   +1 more source

Combination of techniques to quantify the distribution of bacteria in their soil microhabitats at different spatial scales [PDF]

open access: yes, 2018
To address a number of issues of great societal concern at the moment, like the sequestration of carbon, information is direly needed about interactions between soil architecture and microbial dynamics.
Baveye, Philippe C.   +6 more
core   +8 more sources

Chloroplast Fibrillin‐Mediated α‐Tocopherol Biosynthesis Impaired by a Virus to Enhance Infection and to Improve Drought Tolerance

open access: yesAdvanced Science, EarlyView.
ToCV‐encoded p22 targets chloroplast plastoglobules (PGs) via directly binding PG structural protein FBN1.1, reducing the size of PG and inhibiting α‐tocopherol biosynthesis via competing with tocopherol cyclase (VTE1). Consequently, the elevated chloroplast ROS not only creates a suitable cellular environment for efficient ToCV infection but also ...
Sijia Liu   +8 more
wiley   +1 more source

Actividad sinérgica in vitro de los alcaloides Crotsparina y Esparsiflorina aislados de Croton bomplandianum frente a Pseudomonas aeruginosa

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2019
Se evaluó la actividad sinérgica de los alcaloides crotsparina y esparsiflorina, aislados de Croton bomplandianum Baill. con los antibacterianos gentamicina y ciprofloxacina frente a Pseudomonas aeruginosa, microorganismo frecuentemente responsable de ...
Javier García, Nelson Alvarenga
doaj  

Tulpina Pseudomonas fluorescens CNMN-PsB-01 ca potenţial biocontrol asupra fitopatogenilor

open access: yesOne Health & Risk Management, 2023
Introducere. Tulpinile de microorganisme, utilizate în biotehnologie, prezintă valoare economică şi comercială, iar problema menţinerii îndelungate a proprietăţilor lor biosintetice şi economic rămâne în atenţia savanţilor.
Ludmila BALAN (BATÎR)   +2 more
doaj  

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

open access: yesAdvanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao   +12 more
wiley   +1 more source

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