Results 141 to 150 of about 40,029 (216)
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha +12 more
wiley +1 more source
Vaginal host–microbe signatures linked to placental outcomes in mares
Equine Veterinary Journal, EarlyView.Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule +7 more
wiley +1 more source
Diagnosis of bacteraemia in neonatal foals using 16S rRNA high‐throughput sequencing
Equine Veterinary Journal, EarlyView.Abstract Background Sepsis is an important cause of morbidity and mortality in foals. Early diagnosis can improve outcome but is complicated by non‐specific clinical signs and delayed confirmation of infection via blood culture. Molecular assays represent a rapid and more sensitive alternative.
Flavie Payette +7 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Assessing mammary gland health in donkeys is challenging due to the lack of species‐specific diagnostic criteria for subclinical mastitis. Although somatic cell count (SCC) is widely used in dairy ruminants, its diagnostic value in jennies remains unclear.
Anna Rita Attili +8 more
wiley +1 more source
Food Bioengineering, EarlyView.Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu +6 more
wiley +1 more source
Food Chemistry International, EarlyView.Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad +4 more
wiley +1 more source
Food Chemistry International, EarlyView.The graphical abstract represents how natural plant products that preferentially target the specific receptors of quorum sensing could be developed to combat biofilms linked to Yersinia enterocolitica using the potent abilities of protein–ligand complexes with high docking scores.
Rajendran Thomas +7 more
wiley +1 more source
Flavour and Fragrance Journal, EarlyView.Unveiling the potential of Wintergreen (Gaultheria procumbens) essential oil. ABSTRACT This study investigated the antimicrobial, antibiofilm, and insecticidal properties of wintergreen (Gaultheria procumbens L.) essential oil (GPEO). The EO was chemically characterized by GC–MS, confirming methyl salicylate as the predominant compound (99.3%).
Miroslava Kačániová +10 more
wiley +1 more source