Results 141 to 150 of about 753,561 (295)

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew   +8 more
wiley   +1 more source

RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming

open access: yesAngewandte Chemie, EarlyView.
RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh   +3 more
wiley   +2 more sources

Lysyl Oxidase Reduces Neutrophil Extravasation in Response to P. aeruginosa in an Infection‐on‐a‐Chip Model

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo   +7 more
wiley   +1 more source

Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose

open access: yesAngewandte Chemie, EarlyView.
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon   +4 more
wiley   +2 more sources

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam   +8 more
wiley   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis   +9 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

open access: yesHepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole   +12 more
wiley   +1 more source

Corrigendum: <i>Pseudomonas boreofloridensis</i> sp. nov., and <i>Pseudomonas citrulli</i> sp. nov., isolated from watermelon in Florida. [PDF]

open access: yesInt J Syst Evol Microbiol
Fullem KR   +7 more
europepmc   +1 more source

A Comprehensive Review of Microbial Biofilms on Contact Lenses: Challenges and Solutions

open access: yesInfection and Drug Resistance
Adela Voinescu,1– 3 Monica Licker,2,3 Delia Muntean,2,3 Corina Musuroi,2,3 Silvia Ioana Musuroi,1 Oana Izmendi,1,2 Silvana Vulpie,1,2 Romanita Jumanca,4 Mihnea Munteanu,5 Andrei Cosnita5 1Doctoral School “Victor Babes” University of Medicine and Pharmacy,
Voinescu A   +9 more
doaj  

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