Results 201 to 210 of about 734,075 (399)

A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation. [PDF]

open access: yes, 2015
There is a poor understanding of how the physiology of polymicrobial communities in cystic fibrosis (CF) lungs contributes to pulmonary exacerbations and lung function decline.
Bailey, Barbara   +9 more
core   +1 more source

Hydrogel‐Based Smart Materials for Wound Healing and Sensing

open access: yesAggregate, EarlyView.
The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong   +11 more
wiley   +1 more source

Antibacterial size effect of ZnO nanoparticles and their role as additives in emulsion waterborne paint [PDF]

open access: yesarXiv
Nosocomial infections (NIs) are prevalent in intensive care units due to antibiotic overuse. Metal oxide nanoparticles (NPs), like ZnO, offer potential solutions, yet understanding how NPs size impacts their antibacterial efficacy are lacking. This study focuses on the effect of nanoparticle size on kinetics of bacterial strains growth.
arxiv  

Enhanced Synergistic Photothermal–Chemotherapy in Bacterial Keratitis Treatment Using Halogen‐Bonded Organic Frameworks (XOFs) Based on N⋯Br+⋯N Bonds

open access: yesAggregate, EarlyView.
Two novel XOFs based on [N···Br+···N] interactions were constructed. The XOFs(Br) deliver superior antibacterial properties compared with XOFs(I), due to a greater oxidation capability. Moreover, XOF(Br)‐TPPA, exhibiting greater hydrophilicity, shows superior antibacterial properties relative to XOF(Br)‐TPPE, which is weakly hydrophilic.
Zhennan Tian   +13 more
wiley   +1 more source

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

open access: yesAngewandte Chemie, EarlyView.
Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok   +11 more
wiley   +2 more sources

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria

open access: yesAngewandte Chemie, EarlyView.
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur   +7 more
wiley   +2 more sources

Realtime Particulate Matter and Bacteria Analysis of Peritoneal Dialysis Fluid using Digital Inline Holography [PDF]

open access: yesarXiv
We developed a digital inline holography (DIH) system integrated with deep learning algorithms for real-time detection of particulate matter (PM) and bacterial contamination in peritoneal dialysis (PD) fluids. The system comprises a microfluidic sample delivery module and a DIH imaging module that captures holograms using a pulsed laser and a digital ...
arxiv  

Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space

open access: yesAngewandte Chemie, EarlyView.
We optimized mixed peptide‐peptoid sequences for molecular similarity to the macrocyclic lipopeptide antibiotic polymyxin B2 (PMB2) using a genetic algorithm. Synthesis and testing of top‐scoring compounds allowed us to identify new macrocycles with similar antimicrobial activity and reduced toxicity compared to PMB2.
Etienne Bonvin   +7 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy