Results 211 to 220 of about 734,075 (399)

Elexacaftor–Tezacaftor–Ivacaftor Improves Sinonasal Outcomes in Young Children With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Severe chronic rhinosinusitis (CRS) is a near universal manifestation of cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor (ETI) is an oral, small molecule, highly effective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector–potentiator drug.
Amanda L. Stapleton, Adam Kimple, Jennifer L. Goralski, Daniel M. Beswick, Anshika Gupta, Douglas A. Li, Barton F. Branstetter, S. Mehdi Nouraie, Amber D. Shaffer, Brent Senior, Anna C. Zemke   +10 more
wiley   +1 more source

Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota

Angewandte Chemie, EarlyView.
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog, Keishi Ishida, Kirstin Scherlach, Xiuqiang Chen, Benjamin Bartels, Sarah P. Niehs, Bachar Cheaib, Gianni Panagiotou, Christian Hertweck   +8 more
wiley   +2 more sources

A Serological Study on Pseudomonas Aeruginosa Rep. 1. Especially on the Antigenic Structure of Some Mutants Strains of Pseudomonas Aeruginosa

, 1959
Nobuko Matsui
openalex   +2 more sources

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies.

Biotechnology Advances, 2019
Z. Pang, Renee Raudonis, B. Glick, Tong-Jun Lin, Zhenyu Cheng   +4 more
semanticscholar   +1 more source

Beyond the Lung. Impact of Elexacaftor/Tezacaftor/Ivacaftor on Sinonasal Disease in Children With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) is a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) therapy that improves pulmonary function and chronic rhinosinusitis (CRS) in cystic fibrosis (CF) adults with at least one copy of the F508del CFTR mutation.
Margaux Petitjean, Alexia Letierce, Anne‐Sophie Bonnel, Philippe Reix, Eric Deneuville, Nathalie Stremler, Romain Luscan, Vincent Couloigner, Laurent Mely, Katia Bessaci, Guillaume Labbe, Christophe Marguet, Mairead Kelly‐Aubert, Fatiha Hassani, Isabelle Sermet‐Gaudelus, François Simon, the MODUL‐CF Study Group   +16 more
wiley   +1 more source

Functional Silver‐Loaded Porous Composite Scaffold for Bone Tissue Bacterial Infection

Advanced NanoBiomed Research, EarlyView.
In the current study, a AgNP‐loaded gelatin/β‐tricalcium phosphate composite scaffold was developed. Its interconnected porous structure facilitated cell adhesion and proliferation while enhancing osteogenic differentiation‐related gene expression to support bone regeneration.
An'nan Hu, Jian Zhou
wiley   +1 more source

The Behaviour of a Temperate Phage of Pseudomonas aeruginosa compared with that of a Serologically related, Virulent Mutant

, 1954
LÖIS DICKINSON
openalex   +1 more source

Epidemiological Fingerprinting of Pseudomonas aeruginosa by the Production of and Sensitivity to Pyocin and Bacteriophage [PDF]

, 1969
J. J. Farmer, Lloyd G. Herman
openalex   +2 more sources

Measurement and evaluation of the effects of pH gradients on the antimicrobial and antivirulence activities of chitosan nanoparticles in Pseudomonas aeruginosa

Saudi Pharmaceutical Journal, 2018
Objective: The purpose of this study was to study the antimicrobial activity of chitosan nanoparticles (CSNPs) on Pseudomonas aeruginosa with special emphasis on their sensitivity to pH and the effect of pH on their activity.
Fadilah Sfouq Aleanizy, Fulwah Yahya Alqahtani, Gamal Shazly, Rihaf Alfaraj, Ibrahim Alsarra, Aws Alshamsan, Hosam Gareeb Abdulhady   +6 more
doaj  

Investigation of the mating system ofPseudomonas aeruginosastrain 1: V. The effect ofN-methyl-N′-nitro-N-nitrosoguanidine on a donor strain [PDF]

, 1969
J. S. Loutit
openalex   +1 more source