Results 231 to 240 of about 734,075 (399)

Bioinspired Cationic Antimicrobial Polymers

open access: yesAngewandte Chemie International Edition, Accepted Article.
Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of antimicrobial resistance (AMR). Without effective antibiotics, a number of medical advancements from the last century are in jeopardy, threatening our global public health and leading to a high death toll.
Heliya Javadi   +2 more
wiley   +1 more source

Rapid Detection of Pseudomonas Aeruginosa by PCR Method Using Specific Primers of Quorum Sensing LasI gene

open access: yesArmaghane Danesh Bimonthly Journal, 2013
Background & aim: Pseudomonas aeruginosa is an opportunistic nosocomial pathogen that due to having intrinsic and acquired resistance to common antibiotics, mortality due to infections is very common.
H Aghamollaei   +2 more
doaj  

New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Metformin’s pleomorphic effects may be beneficial in sepsis and septic shock, but its impact remains controversial. Our study is the first to show a significant association between metformin and lactate kinetics in sepsis or septic shock, with a larger decrease in lactate after admission.
Nina Van Moorter   +4 more
wiley   +1 more source

Pseudomonas aeruginosa PfpI is a methylglyoxalase. [PDF]

open access: yesJ Biol Chem
Grimm L   +8 more
europepmc   +1 more source

Preparation, Characterization, and Antimicrobial Activities of Ceragenins Incorporated Into Polyvinyl Alcohol/Gelatin/Sodium Alginate‐Based Hydrogels for Treatment of Burn Wounds

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT Ceragenins are synthetic molecules that mimic antimicrobial peptides (AMPs) in the human immune system. They feature a bile acid‐based structure with appended positively charged groups that disrupt bacterial cell membranes, leading to microbial cell death or inactivation.
Nawal Aljayyousi   +6 more
wiley   +1 more source

Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors

open access: yesEuropean Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023
Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley   +1 more source

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