Results 241 to 250 of about 751,645 (378)

Novel Quinazolinones Active against Multidrug‐Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin‐Binding Protein 1A as a Potential Target

open access: yesChemMedChem, EarlyView.
Quinazolinone‐based compounds emerge as potent antimycobacterial agents, showing low minimum inhibitory concentrations against drug‐resistant Mycobacterium tuberculosis. Molecular modeling uncovers a novel allosteric site in PonA1 targeted by these derivatives.
Marek Kerda   +15 more
wiley   +1 more source

Unleashing AdipoRon’s Potential: A Fresh Approach to Tackle Pseudomonas aeruginosa Infections in Bronchiectasis via Sphingosine Metabolism Modulation

open access: yesJournal of Inflammation Research
Jia-wei Xu,1,2,* Fang-fang Chen,1,* Ying-hui Qv,1,* Cong-cong Sun,1 Dong Zhang,1,2 Zhi Guo,1 Yu-jiao Wang,3 Jun-fei Wang,4 Tian Liu,4 Liang Dong,1,2 Qian Qi1,2 1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital
Xu JW   +10 more
doaj  

Rhamnolipid Self‐Aggregation in Water–Bioglycerol Mixtures: Byproduct Valorization for Sustainable Formulation Design

open access: yesChemPlusChem, EarlyView.
Bioglycerol, the primary byproduct of biodiesel production, has the potential to be valorized as a cosolvent in industrial formulations. Surface tension and self‐diffusion data reveal that rhamnolipid self‐aggregation in water is poorly affected by the addition of bioglycerol up to very high concentrations. These results demonstrate that biosurfactants
Rodolfo Esposito   +8 more
wiley   +1 more source

Corticosteroids modulate biofilm formation and virulence of <i>Pseudomonas aeruginosa</i>. [PDF]

open access: yesBiofilm
Jordana-Lluch E   +13 more
europepmc   +1 more source

The hydroxy acids of Pseudomonas aeruginosa 8602 [PDF]

open access: green, 1969
I.C. Hancock   +2 more
openalex   +1 more source

Modular, Tricomponent, and Concurrent One‐Pot Synthesis of Libraries of γ‐Keto Sulfones and γ‐Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures

open access: yesChemSusChem, EarlyView.
This study presents a sustainable, metal‐free, one‐pot synthesis of γ‐keto sulfones and phosphine oxides using a ChCl/p‐TSA·H2O eutectic mixture. The method enables regioselective CC and CX bond formation under mild conditions, aligning with Green Chemistry Principles.
Marina Ramos‐Martín   +2 more
wiley   +1 more source

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