Results 241 to 250 of about 488,525 (347)

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source

A Rapidly Progressive Necrotic Ulcer in an Immunocompromised Patient

JEADV Clinical Practice, EarlyView.
R. Almutairi, H. Alajmi, M. Nouh, F. Alenezi, H. Al‐Sabah, A. Allafi   +5 more
wiley   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Coenzyme A depletion causes antibiotic tolerance in Pseudomonas aeruginosa

Manfredi P, Santi I, Maffei E, Hernandez Gonzalez HA, Conroy S, Lezan E, Ahrnè E, Thürkauf N, van Vliet S, Zamboni N, Schmidt A, Jenal U.   +11 more
europepmc   +1 more source

Antibacterial Micro/Nanorobots: Innovations, Challenges, and Future Perspectives in Combatting Infection

Nano Select, EarlyView.
Antibacterial micro/nanorobots (MNRs) represent a breakthrough in antibacterial therapy, making precise delivery of drugs to the infection site. This review systematically summarizes the material composition, actuation, and applications of MNRs in combating biofilms and drug‐resistant infections while emphasizing the existing challenges of ...
Yichao Chen, Chenlin Jiang, Chuxie Zhang, Wenqing He, Changshun Hou   +4 more
wiley   +1 more source

A novel thermostable YtnP lactonase from Stenotrophomonas maltophilia inhibits Pseudomonas aeruginosa virulence in vitro and in vivo

Jovana Ćurčić, Miroslav Dinić, Katarina Novović, Zorica Vasiljević, Milan Kojić, Branko Jovčić, Milka Malešević   +6 more
openalex   +1 more source

Structural Characterization of Lytic Transglycosylase SltB2 of <i>Pseudomonas aeruginosa</i>. [PDF]

ACS Omega
Miguel-Ruano V, Batuecas MT, Lastochkin E, Domínguez-Gil T, Molina R, Mobashery S, Hermoso JA.   +6 more
europepmc   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Harnessing machine learning to predict antibiotic susceptibility in Pseudomonas aeruginosa biofilms. [PDF]

NPJ Biofilms Microbiomes
Vergauwe F, De Waele G, Sass A, Highmore C, Hanrahan N, Cook Y, Lichtenberg M, Cnockaert M, Vandamme P, Mahajan S, Webb JS, Van Nieuwerburgh F, Bjarnsholt T, Waegeman W, Coenye T.   +14 more
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source