Results 331 to 340 of about 734,075 (399)

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

Antibacterial activity and mechanism of Sodium houttuyfonate against heteroresistant <i>Pseudomonas aeruginosa</i>. [PDF]

Front Microbiol
Li Z, Zhang T, Wang Z, Huang S, Tan C, Wang D, Yuan X, Xu L.   +7 more
europepmc   +1 more source

Quinoline ATP Synthase Inhibitors with Activity Against Multidrug Resistant Acinetobacter baumannii and Pseudomonas aeruginosa

ChemMedChem, EarlyView.
Targeting ATP synthase in Gram‐negative pathogens. Presented is the first disclosure of quinoline‐derived antibiotics inhibiting multidrug resistant Acinetobacter baumannii ATP synthase and expansion of the structure activity relationship profile of Pseudomonas aeruginosa ATP synthase inhibitors.
Katie T. Ward, Alexander P. L. Williams, Angelina L. Dennison, Lena Aamir, Darien L. Allen, Britza Chavez‐Arellano, Toni A. Marchlewski, Mars L. Zappia, Amanda L. Wolfe, P. Ryan Steed   +9 more
wiley   +1 more source

Pseudomonas aeruginosa clinical isolates in Egypt: phenotypic, genotypic, and antibiofilm assessment of Pluronic F-127. [PDF]

BMC Microbiol
Salem MH, Azmy AF, Dishisha T, Dessouky N.   +3 more
europepmc   +1 more source

Novel quinazolinones active against multidrug‐resistant Mycobacterium tuberculosis: synthesis, antimicrobial evaluation and in silico exploration of PonA1 as a potential target

ChemMedChem, Accepted Article.
Quinazolinone derivatives have emerged as promising scaffolds in antimicrobial drug discovery. This work focuses on the design, synthesis, and evaluation of novel quinazolinone‐based compounds and predicts their potential to interact with mycobacterial penicillin‐binding proteins (PBPs).
MAREK KERDA, Daria Nawrot, Petr Slechta, Mirek Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source

Solvent Effect on Antimicrobial Hydrophilic Xerogel Coating of Medicinal Leathers in Simulated Industrial Finishing Process

ChemPlusChem, EarlyView.
Silica‐hyperbranched poly(ethylene imine) (PEI) xerogels incorporating silver nanoparticles coated titanium dioxide particles. Dual solvent dispersions of these composites enhance medical leathers′ hydrophilicity and antimicrobial properties. The nucleation of the metal ions into the dendritic polymer‘s cavities and the gel formation were inspired by ...
Theofanis Bompotis, Eirini Karastergiou, Konstantinos Giannakopoulos, Evangelos P. Favvas, Marina Arvanitopoulou, Konstantinos Arvanitopoulos, Labros Arvanitopoulos, Georgia Kytherioti, Michail Vardavoulias, Dimitrios A. Giannakoudakis, Laura Castellsagués, Sara Maria Soto González., Michael Arkas   +12 more
wiley   +1 more source

Rare presentation of Pseudomonas aeruginosa meningitis following intrathecal pump replacement. [PDF]

Interv Pain Med
Ghaffari C, Reddy R, Furnish T.
europepmc   +1 more source

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy

ChemPlusChem, EarlyView.
Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue, Akihiro Moriyama, Marie Mita, Yue Yu   +3 more
wiley   +1 more source

The Role of Yinqiao Powder in Modulating <i>Pseudomonas aeruginosa</i> Biofilm and Virulence Factors. [PDF]

Infect Drug Resist
Li H, Zhang S, Li Q, Shu Y, Li S, Wu B, Xu Z.   +6 more
europepmc   +1 more source

Quorum-Sensing inhibition by furanone compounds and therapeutic effects on Pseudomonas aeruginosa keratitis rabbit model. [PDF]

BMC Ophthalmol
Dal A, Hekimoğlu R, Sümbül B, Balıbey FB, Gökçe ZÖ, Akbulut E, Elbay A.   +6 more
europepmc   +1 more source