Results 51 to 60 of about 537,193 (355)

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

open access: yesFEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki   +3 more
wiley   +1 more source

Pesquisa de Acinetobacter sp e Pseudomonas aeruginosa produtores de metalo-β-lactamase em hospital de emergência de Porto Alegre, Estado do Rio Grande do Sul, Brasil Investigation of metallo-β-lactamase-producing Acinetobacter sp and Pseudomonas aeruginosa at an emergency hospital in Porto Alegre, State of Rio Grande do Sul, Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUÇÃO: O aparecimento de Pseudomonas aeruginosa e Acinetobacter sp produtores de metalo-β-lactamases (MBLs) é um desafio para os hospitais. MÉTODOS: Verificou-se a produção de MBL em cepas clínicas de Pseudomonas aeruginosa e Acinetobacter sp ...
Vani Dos Santos Laranjeira   +4 more
doaj   +1 more source

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

open access: yesClinical Microbiology Reviews, 2019
In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with ...
Sankalp Malhotra, D. Hayes, D. Wozniak
semanticscholar   +1 more source

Responses of Pseudomonas aeruginosa to antimicrobials [PDF]

open access: yesFrontiers in Microbiology, 2014
Infections caused by Pseudomonas aeruginosa often are hard to treat; inappropriate chemotherapy readily selects multidrug-resistant P. aeruginosa. This organism can be exposed to a wide range of concentrations of antimicrobials during treatment; learning more about the responses of P. aeruginosa to antimicrobials is therefore important.
Yuji Morita   +2 more
openaire   +4 more sources

Nanofillers Reinforcing Biopolymer Composites for Sustainable Food Packaging Applications: A State‐of‐the‐Art Review

open access: yesAdvanced Functional Materials, EarlyView.
Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya   +2 more
wiley   +1 more source

Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistant Pseudomonas aeruginosa

open access: yesInternational Journal of Nanomedicine, 2019
Background The threat of drug-resistant Pseudomonas aeruginosa requires great efforts to develop highly effective and safe bactericide. Objective This study aimed to investigate the antibacterial activity and mechanism of silver nanoparticles (AgNPs ...
Shijing Liao   +10 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Outer Membrane Protein D Gene in Clinical Isolates of Pseudomonas Aeruginosa and its Role in Antibiotic Resistance [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2015
Background & Objectives: Pseudomonas aeruginosa is a common cause of nosocomial infection. OprD protein is a specific protein regulating the uptake of carbapenem antibiotic.
Badrosadat Motaghi, Sohrab Najafipour
doaj  

Genomic and Proteomic Analysis of Pseudomonas aeruginosa Isolated from Industrial Wastewater to Assess Its Resistance to Antibiotics

open access: yesSeparations, 2023
Industrial wastewater usually contains a large amount of organic and inorganic pollutants, and many microorganisms. However, the types of microorganism present in industrial wastewater are still unclear.
Zongwu Wang   +4 more
doaj   +1 more source

Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Mutations in the master quorum-sensing signal receptor LasR are common in Pseudomonas aeruginosa isolated from chronically infected lungs of cystic fibrosis patients.
Maxim Kostylev   +5 more
semanticscholar   +1 more source

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