Results 91 to 100 of about 1,043,348 (245)

pH‐Driven Two‐Stage Conformational Switching Activates an Acid‐Responsive Chaperone

Angewandte Chemie, EarlyView.
AchC is an ATP‐independent, pH‐responsive chaperone. AchC functions as a molecular switch, sensing pH changes and undergoing a two‐stage conformational transition: C‐terminal extension (colored in yellow) loosening at mild pH 4.0–5.5 and monomerization at strong acidic pH 3.0.
Soojeong Ham, Yeon‐Ju Jung, Hyunhee Kim, Sun‐Shin Cha, Changhan Lee   +4 more
wiley   +2 more sources

The Antibiotic Resistance of Pseudomonas spp. Isolated from Different Wards of Shahid Rajai Hospital in Tonekabon, 2010-2011

Medical Laboratory Journal, 2013
: Background and Objective: A wide variety of opportunistic pathogens has been detected in hospital surfaces. Among these , Pseudomonas species are one of the leading causes of nosocomial infections, frequently found in hospital environments. The purpose
SZ Azimi, M Ghane, Z Heshmatipour
doaj  

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

Advanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li, Yilong Yu, Fang Qin, Shenxing Li, Xuanheng Li, Peizhao Liu, Juanhan Liu, Haiqing Liu, Songqi Jing, Jianghao Zou, Sicheng Li, Jiayang Li, Tao Zheng, Yun Zhao, Jianan Ren, Xiuwen Wu   +15 more
wiley   +1 more source

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

Angewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato, Hannah Hunter, Sadhana Srinivasa, Chang‐Hyeock Byeon, Abdulkadir Tunc, Meghan K. Wells, Faith J. Scott, Frederic Mentink‐Vigier, Wook Kim, Sunil Saxena, Ümit Akbey   +10 more
wiley   +2 more sources

DETECTION OF ANTIMICROBIAL RESISTANCE IN NON-FERMENTING BACTERIA ISOLATED FROM WASTEWATER FROM FISH AND POULTRY PROCESSING INDUSTRIES

Brazilian Journal of Infectious Diseases
Introduction/Objective: The “One Health” concept emerged with the objective of highlighting the interconnection between human health, animal health, and environmental health.
Lara Auana da Rosa, Aline Cristina Paulino dos Anjos, Graziela Braun   +2 more
doaj   +1 more source

Global genotype-phenotype correlations in Pseudomonas aeruginosa. [PDF]

, 2010
Once the genome sequence of an organism is obtained, attention turns from identifying genes to understanding their function, their organization and control of metabolic pathways and networks that determine its physiology.
Andreas Dötsch, Pommerenke, Claudia, Pommerenke Claudia, Mathias Müsken, Susanne Häussler, Tanja Becker, Becker, Tanja, Häussler, Susanne, Klawonn Frank, Häussler Susanne, Claudia Pommerenke, Dötsch Andreas, Dötsch, Andreas, Müsken Mathias, Müsken, Mathias, Frank Klawonn, Klawonn, Frank, Becker Tanja   +17 more
core   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Estudo de isolados clínicos de Pseudomonas aeruginosa multirresistentes e produtores de metalo-ß-lactamases [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2011Nas últimas duas décadas, índices crescentes de resistência têm minado a eficácia
Guarneri, Rômulo
core  

Immunoprophylaxis against Klebsiella and Pseudomonas aeruginosa Infections

, 1996
To determine if passive immunization could decrease the incidence or severity of Klebsiella and Pseudomonas aeruginosa infections, patients admitted to intensive care units of 16 Department of Veterans Affairs and Department of Defense hospitals were ...
Bradley, Suzanne, Mulligan, Maury, Kauffman, Carol, Ribner, Bruce, Peduzzi, Peter, Cantey, Robert, Griffiss, J. McLeod, Abrutyn, Elias, Hamadeh, Randa, Federal Hyperimmune Immunoglobulin Trial Study Group, Hamill, Richard J, Leaf, Howard, Gafford, Glenn, Kelly, J. William, Melcher, Gregory P, Cross, Alan S, McClain, J. Bruce, Wallace, Mark, Slagle, David, John, Joseph F, Ellison, Richard T, Elliston, Dan, Young, Edward J, Eliasson, Arn H, Welsh, Carolyn H, Sadoff, Jerald, Schein, Roland M. H, Byrne, W. Russel, Beam, Thomas R, Cryz, Stanley J, Amundson, Dennis, Donta, Sam T, Gumpert, Barton, Johnson, Caroline, Haakenson, Clair   +34 more
core   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

Advanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang, Xin Li, Ying Xiong, Xin Wang, Ying‐Wei Yang   +4 more
wiley   +1 more source