Results 121 to 130 of about 193,010 (259)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Sexual dimorphism in hormone–gut microbiome associations across reproductive states in wild giant pandas

iMetaOmics, EarlyView.
Gut microbiota–host endocrine interactions in wild mammals remain poorly understood. Giant pandas experience seasonal dietary shifts and constrained annual reproduction, offering an ideal model to investigate microbiome–endocrine coupling. We integrated fecal hormone profiling, microsatellite‐based individual identification, and gut microbiome ...
Qinlong Dai, Xinyuan Cui, Chenyi Gao, Xiaoxiao Tang, Kaizhi Wen, Minhui Shi, Chen Zhang, Yue Liu, Xinru Yang, Qiuyu Huang, Lifeng Zhu   +10 more
wiley   +1 more source

Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation. [PDF]

Cell Host Microbe
Durfey SL, Kapnadak SG, Pena T, Willmering MM, Godwin JD, Teresi ME, Heltshe SL, Vo AT, Villacreses RA, Aliukonyte I, Boyken L, Stroik MR, Morgan SJ, Wang GM, Betts HL, Zhang S, Goss CH, Clancy JP, Aitken ML, Steele C, Feder AF, Esther CR, Tiddens HAWM, Woods JC, Stoltz DA, Singh PK.   +25 more
europepmc   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

Biocontrol of Phage Resistance in <i>Pseudomonas</i> Infections: Insights into Directed Breaking of Spontaneous Evolutionary Selection in Phage Therapy. [PDF]

Viruses
Fujiki J, Yokoyama D, Yamamoto H, Kimura N, Shimizu M, Kobayashi H, Nakamura K, Iwano H.   +7 more
europepmc   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

iMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif, Hazrat Bilal, Min Xiao, Lei Dong, Wen‐Jun Li   +4 more
wiley   +1 more source

Therapeutic Interventions for Pseudomonas Infections in Cystic Fibrosis Patients: A Review of Phase IV Trials. [PDF]

J Clin Med
Alqasmi M.
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Nisin-preconditioned mesenchymal stem cells combatting nosocomial Pseudomonas infections. [PDF]

Regen Ther
Enayati S, Halabian R, Saffarian P, Aghamollaei H, Saeedi P.   +4 more
europepmc   +1 more source

Surface Infection with Pseudomonas Aeruginosa

Annals of Surgery, 1964
H L, WALKER, A D, MASON, G L, RAULSTON
openaire   +3 more sources