Intravaginal Progesterone Application as an Efficient and Reproducible Tool for Synchronizing the Mouse Estrous Cycle. [PDF]
ABSTRACT Purpose The synchronization of the estrous cycle is crucial for optimizing reproductive procedures and improving experimental consistency in female mice. Traditional progesterone (P4) administration methods, such as oral or subcutaneous routes, have limitations including invasiveness and variable efficacy.
Sato B +6 more
europepmc +2 more sources
Development, Live Birth and Fertility in Mouse Oocytes Penetrated by Spermatids Exposed to the HDAC Inhibitor Scriptaid. [PDF]
ABSTRACT Purpose In mouse embryos derived from round spermatid injection (ROSI), low developmental potential due to abnormal histone modification is improved by histone deacetylase (HDAC) inhibitors. However, some studies suggest that the use of such inhibitors leads to the birth of hypomorphic offspring.
Watanabe S +9 more
europepmc +2 more sources
Exogenous Lactogenic Signaling Stimulates Beta Cell Replication In Vivo and In Vitro
As patients recently diagnosed with T1D and patients with T2D have residual beta cell mass, there is considerable effort in beta cell biology to understand the mechanisms that drive beta cell regeneration as a potential cellular therapy for expanding ...
Katelyn Millette +4 more
doaj +1 more source
Pseudopregnancy in goats: Sonographic prevalence and associated risk factors in Khartoum State, Sudan [PDF]
Aim: This study was conducted to estimate the prevalence of pseudopregnancy in goats and to investigate potential risk factors associated with the condition in Khartoum State.
Areeg Mohamed Almubarak +5 more
doaj +1 more source
Embryo-Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis. [PDF]
The schematic view shows that embryo‐derived CTSB promotes implantation and decidualization by activating pyroptosis. Blastocyst‐derived CTSB activates NLRP3‐Caspase 1 to cleave GSDMD and cut pro‐IL‐1β/pro‐IL18 to form mature IL‐1β/IL‐18. The cleaved GSDMD‐N perforates the plasma membrane to release mature IL‐1β/IL‐18.
Li MY +7 more
europepmc +2 more sources
Early diagnosis of pseudopregnancy in goats by ultrasonography and response to treatment using cloprostenol sodium [PDF]
Pseudopregnancy is a state of temporary infertility in goats characterised by the accumulation of sterile fluid in the uterus in the absence of a foetus with persistent corpus luteum.
Neema Cherian +4 more
doaj +1 more source
Successful pseudopregnancy of rats by short period artificial stimulation using sonic vibration
Psuedopregnancy for embryo transfer (ET) is usually induced in rats by mating with vasectomized males. Previously, we successfully induced pseudopregnancy using sonic vibration instead (Easy-ET method).
Marina Endo +4 more
doaj +1 more source
. Bunting semu pada kelinci dapat terjadi karena adanya induksi secara hormonal dan stimulasi fisik yang dapat menyebabkan perubahan pada morfologi saluran reproduksi. Salah satu metode induksi bunting semu adalah melalui injeksi GnRH.
Sri Wahyuni +5 more
doaj +1 more source
Incidence of pregnancy loss and characterization of fetal development in red pandas
Previous reports indicate that red pandas (Ailurus fulgens styani) may experience fetal loss during gestation; however, neither the rate nor timing of pregnancy failure has been described in this species.
Jenna Lowe, Erin Curry
doaj +1 more source
Use of urinary 13,14, dihydro-15-keto-prostaglandin F2α (PGFM) concentrations to diagnose pregnancy and predict parturition in the giant panda (Ailuropoda melanolecua). [PDF]
Pregnancy determination is difficult in the giant panda (Ailuropoda melanolecua), representing a challenge for ex situ conservation efforts. Research in other species experiencing pseudopregnancy indicates that urinary/fecal concentrations of 13,14 ...
Beth M Roberts +5 more
doaj +1 more source

