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A murine model of pseudorabies virus latency
Microbial Pathogenesis, 1992The mouse is a useful laboratory animal for studying various aspects of pseudorabies virus (PRV) virulence. Mice are highly susceptible hosts for PRV infection and are unable to survive acute viral infection. Because of this, mouse models have not been useful for studying PRV latent infections.
F A, Osorio, D L, Rock
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Persistence of Pseudorabies Virus in Infected Swine
Journal of the American Veterinary Medical Association, 1980SUMMARY The persistence of pseudorabies virus (prv) in pigs clinically recovered from the disease was detected by culture of tissue fragments. Weanling pigs were infected by intranasal instillation of 200,000 plaque-forming units of a strain of prv isolated from sick pigs in Iowa, and virus was recovered from them 6 weeks to 13 months later.
G W, Beran +5 more
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A pseudorabies virus-specific sulfated moiety
Virology, 1976Abstract Pronase digestion of the sulfated proteins excreted from pseudorabies virus-infected rabbit kidney cells produces sulfated fragments that are retarded on Sephadex G-50 columns to the same extent as the amino acid fragments. The sulfated fragments can be further fractionated by Sephadex G-10 chromatography which gives rise to a 35 S-labeled ...
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Molecular Biology of Pseudorabies Virus
1985Pseudorabies virus (PRV) causes a natural infection in swine similar to that of herpes simplex virus (HSV) in man, and B virus in monkeys. Sabin (1934) was the first to recognize that these viruses are naturally related. As Sabin put it, “Their generic relationship may perhaps be based on the following properties, which, taken together, are not ...
Tamar Ben-Porat, Albert S. Kaplan
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Photoreactivation of pseudorabies virus
Virology, 1965E R, Pfefferkorn +2 more
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Pseudorabies Virus (Herpesviridae)
2021Thomas C. Mettenleiter, Barbara G. Klupp
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Molecular biology of pseudorabies (Aujeszky's disease) virus
Comparative Immunology, Microbiology and Infectious Diseases, 1991In this review, some of the aspects concerning the molecular biology of pseudorabies virus (PrV), the causative agent of Aujeszky's disease, will be discussed. It will mainly focus on new findings concerning viral glycoproteins, factors determining PrV virulence, the problem of PrV latency and the development regarding genetically engineered vaccines.
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