Results 1 to 10 of about 10,558 (183)

Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon [PDF]

Vaccines, 2021
Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar).
Muhammad Salman Malik, Lena H. Teige, Stine Braaen, Anne Berit Olsen, Monica Nordberg, Marit M. Amundsen, Kannimuthu Dhamotharan, Steingrim Svenning, Eva Stina Edholm, Tomokazu Takano, Jorunn B. Jørgensen, Øystein Wessel, Espen Rimstad, Maria K. Dahle   +13 more
doaj   +6 more sources

Aminoquinoline surfen inhibits pseudorabies virus attachment by preventing the binding of glycoprotein C to heparan sulfate [PDF]

Microbiology Spectrum
Pseudorabies virus (PRV) is an important herpesvirus that infects pigs and many other animals. PRV can also infect humans, but the relevant reports are still very rare. PRV is not only a serious concern in veterinary medicine, but also a potential threat
Yiping Wang, Binbin Zhu, Xinyi Huang, Fei Zhao, Zhiyuan Zheng, Senhong Zhao, Xiaobo Huang, Yi Zheng, Qin Zhao, Yiping Wen, Rui Wu, Senyan Du, Chun Wu, Tongqing An, Sanjie Cao   +14 more
doaj   +2 more sources

PRV-delgE/gI/TK immunization preserves blood–brain barrier integrity and limits CNS injury following intracerebral PRV challenge [PDF]

Microbiology Spectrum
Pseudorabies virus (PRV) causes rapidly progressive and often fatal encephalitis in both natural and non-natural hosts, making the development of effective preventive strategies critically important.
Tong Xu, Baoling Liu, Hanyu Li, Lei Zhao, Yangming Dai, Xin Wu, Siyuan Lai, Jian-Bo Huang, Zhi-Wen Xu, Ling Zhu   +9 more
doaj   +2 more sources

Virulence, pathology, and pathogenesis of Pteropine orthoreovirus (PRV) in BALB/c mice: Development of an animal infection model for PRV. [PDF]

PLoS Neglected Tropical Diseases, 2017
Cases of acute respiratory tract infection caused by Pteropine orthoreovirus (PRV) of the genus Orthoreovirus (family: Reoviridae) have been reported in Southeast Asia, where it was isolated from humans and bats.
Kazutaka Egawa, Masayuki Shimojima, Satoshi Taniguchi, Noriyo Nagata, Hideki Tani, Tomoki Yoshikawa, Takeshi Kurosu, Shumpei Watanabe, Shuetsu Fukushi, Masayuki Saijo   +9 more
doaj   +4 more sources

Human infection with pseudorabies virus: review of evidence, risk assessment, and future directions [PDF]

Journal of Virology
Pseudorabies virus (PRV) is an alphaherpesvirus with a broad host range, with the pig as its natural host. Although PRV can use human cell surface receptors for cell entry, humans and higher primates have been considered as refractory or showing very ...
Herman W. Favoreel
doaj   +2 more sources

Molecular and Antigenic Characterization of Piscine orthoreovirus (PRV) from Rainbow Trout (Oncorhynchus mykiss)

Viruses, 2018
Piscine orthoreovirus (PRV-1) causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). Recently, a novel PRV (formerly PRV-Om, here called PRV-3), was found in rainbow trout (Oncorhynchus mykiss) with HSMI-like ...
Torstein Tengs, Argelia Cuenca, Espen Rimstad   +2 more
exaly   +3 more sources

Pseudorabies virus (PRV) strain with defects in gE, gC, and TK genes protects piglets against an emerging PRV variant

Journal of Veterinary Medical Science, 2020
The prevalence of an emerging variant of the pseudorabies virus (PRV) has been causing serious losses to farmers in China. Moreover, the commercially available PRV vaccine often fails to provide thorough protection. Therefore, in this study, we generated a PRV-∆gC\gE∆TK strain with defects in gC, gE, and TK of PRV.
Zhihua Feng, Jinxin Lin
exaly   +4 more sources

Evasion of the Antiviral Innate Immunity by PRV

International Journal of Molecular Sciences
Pseudorabies virus (PRV) establishes persistent latent infections by effectively evading the host’s antiviral innate immune response. PRV has developed sophisticated strategies to bypass immune surveillance through coevolution with its host. Currently, no effective vaccine exists to prevent or treat infections caused by emerging PRV variants, and the ...
Huimin Liu, Hongtao Chang, Xinyu Zhai
exaly   +3 more sources

Isolation and Characterization of Two Pseudorabies Virus and Evaluation of Their Effects on Host Natural Immune Responses and Pathogenicity

Viruses, 2022
Pseudorabies, caused by the pseudorabies virus (PRV), is an acute fatal disease, which can infect rodents, mammals, and other livestock and wild animals across species.
Qiongqiong Zhou, Longfeng Zhang, Hongyang Liu, Guangqiang Ye, Li Huang, Changjiang Weng   +5 more
doaj   +1 more source

(−)-Epigallocatechin-3-Gallate Inhibits the Life Cycle of Pseudorabies Virus In Vitro and Protects Mice Against Fatal Infection

Frontiers in Cellular and Infection Microbiology, 2021
A newly emerged pseudorabies virus (PRV) variant with enhanced pathogenicity has been identified in many PRV-vaccinated swine in China since 2011. The PRV variant has caused great economic cost to the swine industry, and measures for the effective ...
Changchao Huan, Changchao Huan, Changchao Huan, Weiyin Xu, Weiyin Xu, Weiyin Xu, Tingting Guo, Haochun Pan, Haochun Pan, Haochun Pan, Hengyue Zou, Hengyue Zou, Hengyue Zou, Luyao Jiang, Luyao Jiang, Luyao Jiang, Chengmin Li, Song Gao, Song Gao, Song Gao, Song Gao   +20 more
doaj   +1 more source