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The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans

open access: yesViruses, 2022
Pseudorabies virus (PRV) can infect most mammals and is well known for causing substantial economic losses in the pig industry. In addition to pigs, PRV infection usually leads to severe itching, central nervous system dysfunction, and 100% mortality in ...
Qingyun Liu   +9 more
doaj   +3 more sources

Comparative Transcriptomic Analysis Reveals Divergent Host Cell Responses to Classical and Variant Pseudorabies Virus Strains [PDF]

open access: yesVeterinary Sciences
Pseudorabies virus (PRV), also called suid alphaherpesvirus 1, is a double-stranded linear DNA virus belonging to the subfamily Alphaherpsvirinae of the family Herpesviridae [...]
Zihan Yang   +9 more
doaj   +2 more sources

Antiviral activity of nitazoxanide against pseudorabies virus infection in vitro [PDF]

open access: yesFrontiers in Veterinary Science
Pseudorabies (PR), an infectious disease caused by pseudorabies virus (PRV), has been responsible for substantial economic losses within the global swine industry.
Lei Tan   +12 more
doaj   +2 more sources

RR1 and RR2 gene deletion affects the immunogenicity of a live attenuated pseudorabies virus vaccine candidate in natural pig host [PDF]

open access: yesFrontiers of Agricultural Science and Engineering, 2016
As virulence-determining genes, RR1 and RR2 encode the small subunit and large subunit of viral ribonucleotide reductase (RR) in pseudorabies virus which have been extensively studied in mice.
Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN
doaj   +1 more source

Cross species transmission of pseudorabies virus leads to human encephalitis and visual impairment: A case report

open access: yesFrontiers in Neurology, 2022
Pseudorabies virus (PRV) is a common pig infectious disease. There have been few reports of PRV infection in humans. The patient in this article had acute onset, which was manifested by fever, epilepsy, disturbance of consciousness, and other symptoms ...
Hui Huang   +5 more
doaj   +1 more source

Research Progress in Active Components of Plant Extracts Resistant to Pseudorabies Virus

open access: yesGuangdong nongye kexue, 2022
Pseudorabies is a hot infectious disease, which can cause fever, encephalomyelitis, multiple organ failure, paralysis and other symptoms in infected animals.
Yuanjie FANG   +5 more
doaj   +1 more source

Pseudorabies Virus Infections

open access: yesPathogens, 2021
Suid alphaherpesvirus 1 (SuHV-1), better known as Pseudorabies virus (PrV), an alphaherpesvirus of swine, is the causative agent of Aujeszky’s Disease [...]
Barbara G. Klupp
doaj   +1 more source

Global asymptotic stability in a pseudorabies virus model with age structure

open access: yesInfectious Disease Modelling, 2023
Pseudorabies is a highly contagious disease caused by pseudorabies virus (PRV) or suid herpesvirus 1 (SuHV1), causing significant economic losses to the swine industry in countries where the disease exists.
Yining Chen, Yuhua Long, Jianshe Yu
doaj   +1 more source

Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

open access: yesFrontiers in Veterinary Science, 2022
In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011.
Shijun Yan   +9 more
doaj   +1 more source

A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing

open access: yesBMC Neurology, 2023
Background Pseudorabies virus (PRV) was thought to only infect animals. Recent studies have shown that it can also infect human. Case presentation We report a case of pseudorabies virus encephalitis and endophthalmitis, diagnosed 89 days after onset ...
Yi Zhang   +6 more
doaj   +1 more source

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