Results 31 to 40 of about 9,158 (116)

A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant

open access: yesBMC Veterinary Research, 2019
Background Since 2011, pseudorabies caused by a variant PRV has re-emerged in many Chinese Bartha-K61-vaccinated pig farms. An efficacious vaccine is necessary to control this disease.
Chuanjian Zhang   +9 more
doaj   +1 more source

A Solution with Ginseng Saponins and Selenium as Vaccine Diluent to Increase Th1/Th2 Immune Responses in Mice

open access: yesJournal of Immunology Research, 2020
Pseudorabies is an important infectious disease of swine, and immunization using attenuated pseudorabies virus (aPrV) vaccine is a routine practice to control this disease in swine herds.
Yong Wang   +7 more
doaj   +1 more source

Pathogenicity characteristics of different subgenotype pseudorabies virus in newborn piglets

open access: yesFrontiers in Veterinary Science
Pseudorabies virus is a major pathogen in the pig industry, causing substantial economic losses. The emergence of pseudorabies virus variant strains in China has led to extensive spread, raising concerns about their potential impact.
Lei Xu   +9 more
doaj   +1 more source

Tk-deleted pseudorabies virus retains high pathogenicity in rats

open access: yesJournal of Veterinary Research, 2021
The pseudorabies virus (PRV) gene encoding thymidine kinase (tk) is an important virulence-associated factor. Attenuation of PRV in susceptible animals is a frequent result of tk deletion.
Zhang Lirong   +11 more
doaj   +1 more source

Effects of physical and chemical factors on pseudorabies virus activity in vitro

open access: yesBMC Veterinary Research, 2020
Background Pseudorabies (PR) is latent and can persist in infected sows for a long time, and thus, convalescent sows can carry the virus throughout life, causing severe economic losses to farmers and posing a tremendous challenge to PR prevention and ...
Lang Gong   +5 more
doaj   +1 more source

Emodin as an Inhibitor of PRV Infection In Vitro and In Vivo

open access: yesMolecules, 2023
Pseudorabies (PR) is an acute and severe infectious disease caused by pseudorabies virus (PRV). Once the virus infects pigs, it is difficult to eliminate, resulting in major economic losses to the global pig industry.
Xiaojing Cai   +7 more
doaj   +1 more source

CRISPR/Cas9-based generation of a recombinant double-reporter pseudorabies virus and its characterization in vitro and in vivo

open access: yesVeterinary Research, 2021
Pseudorabies, caused by pseudorabies virus (PRV) variants, has broken out among commercial PRV vaccine-immunized swine herds and resulted in major economic losses to the pig industry in China since late 2011.
Peng-Fei Fu   +8 more
doaj   +1 more source

Aujeszky’s Disease in South-Italian Wild Boars (Sus scrofa): A Serological Survey

open access: yesAnimals, 2021
Aujeszky’s disease (AD, pseudorabies) is a viral disease of suids caused by Suid Herpesvirus 1 (SHV-1) also referred as Aujeszky’s disease virus (ADV) or Pseudorabies virus (ADV).
Gianmarco Ferrara   +10 more
doaj   +1 more source

Recombinant pseudorabies virus with gI/gE deletion generated by overlapping polymerase chain reaction and homologous recombination technology induces protection against the PRV variant PRV-GD2013

open access: yesBMC Veterinary Research, 2021
Background Since 2011, numerous highly virulent and antigenic variant viral strains have been reported in pigs that were vaccinated against the swine pseudorabies virus.
Wenhui Li   +7 more
doaj   +1 more source

Pseudorabies detected in hunting dogs in Alabama and Arkansas after close contact with feral swine (Sus scrofa)

open access: yesBMC Veterinary Research, 2018
Background Pigs (Sus scrofa) are the natural hosts of pseudorabies virus (PRV), also known as Aujeszky’s disease. Infection in mammals, with the exception of humans, typically causes extreme itching, facial swelling, and excessive salivation, followed by
Kerri Pedersen   +5 more
doaj   +1 more source

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