Results 41 to 50 of about 9,158 (116)

A novel recombinant pseudorabies virus expressing parvovirus VP2 gene: Immunogenicity and protective efficacy in swine

open access: yesVirology Journal, 2011
Background Porcine parvovirus (PPV) VP2 gene has been successfully expressed in many expression systems resulting in self-assembly of virus-like particles (VLPs) with similar morphology to the native capsid.
Chen Dishi   +8 more
doaj   +1 more source

An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

open access: yesJournal of Immunology Research, 2014
Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus ...
Bo Dong, Dante S. Zarlenga, Xiaofeng Ren
doaj   +1 more source

Screening and Stability Evaluation of Freeze-Dried Protective Agents for a Live Recombinant Pseudorabies Virus Vaccine

open access: yesVaccines
Infection of pigs with the pseudorabies virus (PRV) causes significant economic losses in the pig industry. Immunization with live vaccines is a crucial aspect in the prevention of pseudorabies in swine.
Yan Liu   +10 more
doaj   +1 more source

TLR Agonist Immunoadjuvants Provide Effective Protection Against PCV2 and PRV Infections in a Bivalent Subunit Vaccine for PCV2 and PRV

open access: yesVeterinary Sciences
Diseases associated with porcine circovirus type 2 (PCV2) and pseudorabies virus (PRV) significantly affect the economy of pig farms, particularly when combined infections lead to bacterial co-infections.
Fulai Yu   +5 more
doaj   +1 more source

Aptamer-Based QCM-Sensor for Rapid Detection of PRRS Virus

open access: yesProceedings, 2018
Porcine reproductive and respiratory syndrome (PRRS) is caused by an RNA virus and has substantial economic impact on swine industry. Screening pigs for infection is the best way to prevent spreading the disease. For that purpose, we developed biosensors
Chakpetch Kuitio   +2 more
doaj   +1 more source

Age-dependent differences in type I interferon, IL-12 and pro-inflammatory cytokine production by porcine peripheral blood mononuclear cells in response to pseudorabies virus-infected cells

open access: yesFrontiers in Immunology
Pseudorabies virus is a porcine alphaherpesvirus that causes devastating disease with high mortality in young piglets but much milder, mainly respiratory, problems in older pigs.
Manon S. C. Claeys   +4 more
doaj   +1 more source

The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets

open access: yesFrontiers in Microbiology
Compared to the classical strain of Pseudorabies virus (PRV), the PRV variant exhibits stronger transmissibility and pathogenicity, causing immense disasters for the global pig industry. Based on this variant, our laboratory has preliminarily constructed
Yang Zhang   +11 more
doaj   +1 more source

Fast and sensitive differential diagnosis of pseudorabies virus-infected versus pseudorabies virus-vaccinated swine using CRISPR-Cas12a

open access: yesMicrobiology Spectrum
Pseudorabies virus (PRV) is the causative pathogen of Aujeszky’s disease. It causes high mortality and miscarriage rates in the infected swine, leading to tremendous economic losses in the global swine industry.
Hao Wang   +7 more
doaj   +1 more source

Getah Virus: A New Contaminant in Veterinary Vaccines

open access: yesVeterinary Sciences
Mycoplasma, reticuloendotheliosis virus (REV), avian leukosis virus (ALV), chicken infectious anemia virus (CIAV), bovine polyomavirus (BPV), bovine viral diarrhea virus (BVDV), and porcine circovirus (PCV) are considered common contaminants in live ...
Pin-Pin Chu   +4 more
doaj   +1 more source

Analysis of the recombination and evolution of the new type mutant pseudorabies virus XJ5 in China

open access: yesBMC Genomics
Pseudorabies have caused enormous economic losses in China’s pig industry and have recurred on many large pig farms since late 2011. The disease is caused by highly pathogenic, antigenic variant pseudorabies virus (vPRV) strains.
Luyao Jiang   +11 more
doaj   +1 more source

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