Results 81 to 90 of about 11,544 (218)

Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus [PDF]

, 1992
The gene encoding glycoprotein B (gB) of murine cytomegalovirus (MCMV) strain Smith was identified, sequenced, and expressed by recombinant vaccinia virus.
Rapp, Maria, Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Keil, Günther M., Tannheimer, Michael   +5 more
core  

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, Volume 604, Issue 4, Page 1547-1557, 15 February 2026.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang, Jing Ren, Yawen Wang, Chen Yuan, Tairan Sun, Jinhai Huang, Qinye Song, Nan-hua Chen   +7 more
wiley   +1 more source

A serological survey and the diagnosis of pseudorabies virus among pigs in Argentina [PDF]

, 2023
An enzyme linked immunosorbent assay (blocking ELISA) was used to detect antibodies to pseudorabies virus (PRV) in serum samples from 5955 pigs. The results of this test indicated that 10.5% of the samples were positive to pseudorabies.
Belak, K., Gimeno, Emilio Juan, Etcheverrigaray, María Elisa, Fonrouge, Reinaldo Domingo, Nosetto, Edgardo Omar, Galosi, Cecilia Mónica, Echeverría, María Gabriela, Pereyra, N. B.   +7 more
core  

An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

Journal of Immunology Research, 2014
Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus ...
Bo Dong, Dante S. Zarlenga, Xiaofeng Ren
doaj   +1 more source

Regulation of the vhs gene promoter of pseudorabies virus by IE180 and EP0, and the requirement of a Sp1 site for the promoter function

, 2014
The virion host shutoff (vhs) protein is a virion component of Alphaherpesviruses, including pseudorabies virus. In this work, the upstream sequences of vhs gene of pseudorabies virus (TNL strain) was cloned and sequenced.
Chang, Y.Y., Chang, T.J., Lin, H.W., Wong, M.L., 張天傑   +4 more
core   +1 more source

A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB. [PDF]

, 2010
Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 ...
Stewart, James P., Stipan, J., Adler, Heiko, James P Stewart, Adler Barbara, Adler, Barbara, Heiko Adler, Beatrix Steer, Barbara Adler, Jonjic Stipan, Stipan Jonjic, Steer, Beatrix, Steer Beatrix, Steer, B., Adler Heiko, Stewart James P., Adler, H., Adler, B., Jonjic, Stipan, James P. Stewart, Stewart, J.P.   +20 more
core   +1 more source

Protection of pigs against pandemic swine origin H1N1 influenza A virus infection by hemagglutinin- or neuraminidase-expressing attenuated pseudorabies virus recombinants

, 2015
Influenza is an important respiratory disease of pigs, and may lead to novel human pathogens like the 2009 pandemic H1N1 swine-origin influenza virus (SoIV). Therefore, improved influenza vaccines for pigs are required.
Fuchs, Walter, Lange, Elke, Mettenleiter, Thomas C., Klingbeil, Katharina, Teifke, Jens Peter, Blohm, Ulrike   +5 more
core   +1 more source

Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure

, 2002
Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life. Wild-type serotype 1 IBDV strains
Peeters, B.P.H., ter Huurne, A.A.H.M., Pol, J.M., Hoekman, A.J.W., Huurne, A.A.H.M., ter, Boot, H.J., Gielkens, A.L.J.   +6 more
core   +1 more source