Results 51 to 60 of about 1,021 (158)

Purification and Composition of Polysaccharides from Pseudostellaria heterophylla and Protective Effect on Raw 264.7 Cells Induced by LPS

Shipin gongye ke-ji, 2022
To determine the composition and protective effect on Raw 264.7 cells of polysaccharide from Pseudostellaria heterophylla as a traditional Chinese medicinal, the main active ingredient-Pseudostellaria heterophylla polysaccharide (PHP) was extracted by ...
Meilin XIE, Haiqing XU, Jingming LI, Daoxi ZHA, Xueying WANG, Yang CHEN, Qifa ZHU   +6 more
doaj   +1 more source

Fuzheng Jiedu Decoction Induces Apoptosis and Enhances Cisplatin Efficacy in Ovarian Cancer Cells In Vitro and In Vivo through Inhibiting the PI3K/AKT/mTOR/NF‐κB Signaling Pathway

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Objectives. This study is aimed at investigating the anticancer activity of Fuzheng Jiedu decoction (FJD) alone or in combination with cisplatin in ovarian cancer (OC) models, as well as its underlying mechanisms of action. Methods. The anticancer activities of FJD, cisplatin, and the combination of the PI3K inhibitor (LY294002, LY) or activator (IGF‐1)
Huadi Yang, Hui Li, Shenyi Lu, Shuangshuang Shan, Yong Guo, Vasiliki Galani   +5 more
wiley   +1 more source

Oral Realgar‐Indigo Naturalis Formula Treatment for Acute Promyelocytic Leukemia in Children: A Randomized, Control Clinical Trial

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Objective. To analyze the efficacy, safety, and economy of RIF compared with intravenous arsenic trioxide (ATO) for the induction and consolidation therapy of pediatric APL. Materials and Methods. In this randomized control clinical trial (NCT02200978), children with newly diagnosed APL from June 2013 to December 2017 were randomly divided into RIF and
Senlin Luo, Jidong Tian, Xiao Sun, Feifeng Wu, Ying Liu, Wuqing Wan, Zhou She, Chuan Wen, Chan-Yen Kuo   +8 more
wiley   +1 more source

Bushen Jianpi Quyu Formula Alleviates Myelosuppression of an Immune‐Mediated Aplastic Anemia Mouse Model via Inhibiting Expression of the PI3K/AKT/NF‐κB Signaling Pathway

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Bushen Jianpi Quyu Formula (BSJPQYF), an experienced formula, has been used to treat aplastic anemia (AA) more than three decades. To determinate the effect of BSJPQYF on AA, we constructed an immune‐mediated AA mouse model. All mice were divided into four groups: control, model, low dose (0.85 g/mL), and high dose (1.7 g/mL BSJPQYF) group.
Hangchao Li, Lina Ji, Yingying Shen, Danqing Fu, Dijiong Wu, Baodong Ye, Jian-You Guo   +6 more
wiley   +1 more source

“Jing‐Ning Granules” Can Alleviate Attention Deficit Hyperactivity Disorder in Rats by Modulating Dopaminergic D2/D1‐Like Receptor‐Mediated Signaling Pathways

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Background. Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by attention deficit, hyperactivity, and impulsivity. Jing‐Ning Granules (JNG) is a traditional Chinese medicine (TCM) that can alleviate ADHD.
Jie Ding, Yiyun Ding, Jingjing Wu, Jialin Deng, Qingyang Yu, Junhong Wang, K. Rajeev Singla   +6 more
wiley   +1 more source

The TCM Prescription Yi‐Fei‐Jie‐Du‐Tang Inhibit Invasive Migration and EMT of Lung Cancer Cells by Activating Autophagy

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Yi‐Fei‐Jie‐Du‐Tang (YFJDT) is a traditional Chinese medicine formulation. Our previous studies have demonstrated that YFJDT can be used to treat non‐small‐cell lung cancer (NSCLC), but its protective effect against NSCLC and its mechanisms remain unclear.
Shanshan Wang, Zaichuan Wang, Yinqiu Wu, Chao Hou, Xiaojun Dai, Qingyin Wang, Yongjian Wu, Chao Qian, Xiaochun Zhang, Meng-Shih Weng   +9 more
wiley   +1 more source

HPLC‐MS and Network Pharmacology Analysis to Reveal Quality Markers of Huo‐Xue‐Jiang‐Tang Yin, a Chinese Herbal Medicine for Type 2 Diabetes Mellitus

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Huo‐Xue‐Jiang‐Tang Yin (HXJTY) is a Chinese medicine formulation, which has been widely used for the treatment of various lipometabolism‐ and glycometabolism‐related diseases in clinics. Currently, HXJTY is mainly prescribed to treat patients with type 2 diabetes mellitus (T2DM), yet its chemical and pharmacologic profiles remain to be elucidated. Here,
Qiugu Chen, Yuan Zhao, Maosheng Li, Ping Zheng, Shangbin Zhang, Huilin Li, Jianping Chen, Maria Grazia Ferraro   +7 more
wiley   +1 more source

Sheng Jing Decoction Can Promote Spermatogenesis and Increase Sperm Motility of the Oligozoospermia Mouse Model

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Sheng Jing Decoction (SJD), as a traditional Chinese medicine prescription, is mainly be used to treat male infertility. However, the pharmacological functions and molecular mechanisms of SJD are poorly understood. In this study, we investigated the functions of SJD on spermatogenesis and sperm motility and explored the potential mechanisms involved ...
Guang Yan, Fang Tian, Peng Liu, Jianming Sun, Jianmin Mao, Wenjun Han, Ran Mo, Shishuai Guo, Quanyao Yu, Mateus R. Beguelini   +9 more
wiley   +1 more source

Cyclic Peptide Extracts Derived From Pseudostellaria heterophylla Ameliorates COPD via Regulation of the TLR4/MyD88 Pathway Proteins. [PDF]

Front Pharmacol, 2020
Lu F, Yang H, Lin SD, Zhao L, Jiang C, Chen ZB, Liu YY, Kan YJ, Hu J, Pang WS.   +9 more
europepmc   +3 more sources

Two Nitrogen-containing Compounds from Pseudostellaria heterophylla [PDF]

Natural Product Communications, 2018
Two new nitrogen-containing compounds, pseudosteheterins A (1) and B (2), were isolated from the glycosides-enriched cardioprotective fraction of the 70% EtOH extract of the roots of Pseudostellaria heterophylla. Their structures were elucidated by spectroscopic methods, and the absolute configuration of 1 was established by quantum chemical TDDFT ...
Xiang-Ming Liao, Xun He, Guo-Bo Xu, Zhen Wang, Jing Li, Huan-Yu Guan, Meng Zhou, Yong-Jun Li, Yong-Lin Wang, Li-She Gan, Shang-Gao Liao   +10 more
openaire   +1 more source