Results 171 to 180 of about 360,646 (291)

Biosensor Based on pSi-SU-8-GQD Heterostructures for Enhanced Viral Detection by Dual Signal Amplification Strategy. [PDF]

ACS Omega
Popescu MA, Gogianu LI, Mihalache I, Ion V, Petrescu S, Damian CM, Vasile BS, Popescu MC, Boldeiu A, Gorecki GP, Simion ML.   +10 more
europepmc   +1 more source

Time‐Resolved SAXS Reveals Distinct Millisecond Metal‐Induced Conformational Dynamics of Monomeric α‐Synuclein

Advanced Science, EarlyView.
Time‐resolved SAXS reveals how physiologically relevant metal ions shape the earliest conformational responses of monomeric α‐synuclein. Fe3+ induces rapid compaction, Cu2+ generates heterogeneous and partially folded ensembles, while Mn2+ and Zn2+ cause only modest changes.
Rebecca Sternke‐Hoffmann, Miriam Dos Santos Pinto, Xue Wang, Jinghui Luo   +3 more
wiley   +1 more source

Structural basis of diadinoxanthin-Chl a/b-binding proteins in the photosystem I supercomplex of <i>Euglena gracilis</i>. [PDF]

Sci Adv
Bai T, Mao Z, Sun D, Tang Y, Lu Z, Ma F, Ma B, Chen J, Wang W, Li Y, Liu S, Yang Y, Wang Y, Tian L.   +13 more
europepmc   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Machine learning framework for mRNA alternative splicing analysis identifies a signature of progression in colorectal adenocarcinoma. [PDF]

Sci Rep
Maimekov U, Nosrati M, Mahmoud A, Mustafi M, Craige MW, Coffman F, Parrott JS, Lutz C, Mitrofanova A.   +8 more
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Design and Characterization of DX‐Tile DNA Nanostar‐Based Hydrogels

Advanced Science, EarlyView.
In this study, the authors demonstrated that DNA DX‐tile‐based multi‐arm motifs can be used to assemble pure DNA hydrogels, offering greater design flexibility and enhanced control over their mechanical properties and functionalization capabilities compared to single duplex‐based DNA hydrogels.
Dylan V. Scarton, Alessandra B. Coogan, Peter M. Touma, Eray O. Tulun, Katie A. Harrison, Jack Buchen, Richard C. Steiner, Christopher R. Fellin, Hunter G. Mason, Chih‐Hsiang Hu, Sally Farag, Xiaoning Yuan, Shailly Jariwala, Remi Veneziano   +13 more
wiley   +1 more source

Mapping the Mind: A Network Meta-Analysis of Mindfulness and Traditional and Digital Interventions for Cognitive and Behavioral Enhancement in Children With Attention-Deficit/Hyperactivity Disorder (ADHD). [PDF]

Cureus
Hassan Awaji HH, Alharbi RA, Mokli MB, Balawi GM, ALzahrani YS, Khan AR, Bima TA, Atwie MG, Alatwai AO, Alatawi SA, Albalawi RM.   +10 more
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Two types of Wechsler Adult Intelligence Scale (WAIS) index discrepancies are associated with insufficient weight reduction after sleeve gastrectomy in adult patients with obesity: a retrospective study. [PDF]

Eur J Med Res
Ohira M, Tsuji S, Watanabe Y, Horikawa O, Kawagoe N, Nabekura T, Hashi K, Hayashi K, Nagayama D, Tatsuno I, Oshiro T, Saiki A.   +11 more
europepmc   +1 more source