Results 31 to 40 of about 27,590 (176)

Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi, Tiago Azzi, Agustina Legaz, David Aguillón, José Alberto Avila‐Funes, Maria Isabel Behrens, Martín Bruno, Juan Felipe Cardona, Nilton Custodio, Carolina Delgado, Stefanie Pina‐Escudero, Maria del Pilar Garavito Galofre, Marcelo Maito, Nahuel Magrath‐Guimet, Justin B. Miller, Diana Matallana, Maira Okada de Oliveira, Guido Rocatti, Elisa de Paula França Resende, Andrea Slachevsky, Leonel Takada, Olivia Wen, Lina M. Zapata‐Restrepo, Brian Lawlor, Kristine Yaffe, Kun Hu, Bruce Miller, Katherine Possin, Jennifer S. Yokoyama, Sol Fittipaldi, Adolfo M. García, Hernan Hernandez Larzabal, Hernando Santamaria‐Garcia, Enzo Tagliazzuchi, Claudia Duran‐Aniotz, Agustin Ibanez, Joaquin Migeot   +36 more
wiley   +1 more source

Patologia psiquiátrica nos cuidados primários de saúde

Revista Portuguesa de Medicina Geral e Familiar, 2008
É consensual a alta prevalência de patologia psiquiátrica ao nível dos Cuidados de Saúde Primários. Consensual será também o papel fulcral que estes mesmos Cuidados desempenham enquanto primeiro filtro na abordagem dos problemas psiquiátricos ...
João Amílcar Teixeira, Ana Sofia Cabral   +1 more
doaj   +1 more source

Estatística em psiquiatria [PDF]

Revista Brasileira de Psiquiatria, 2001
Este artigo apresenta os paradigmas do processo de pesquisa que utilizam a análise de dados. Indica como os avanços da computação influíram no processo, permitindo a análise de sistemas complexos. Na psiquiatria, são indicadas algumas áreas onde a estatística tem papel importante e como a colaboração entre psiquiatras e estatísticos pode ser ...
openaire   +2 more sources

White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2‐adrenergic receptor expression

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION White matter hyperintensities (WMHs) are a robust marker of brain aging and dementia risk, typically attributed to vascular pathology. However, impaired astrocytic support may also contribute. The locus coeruleus (LC), which degenerates early in aging and Alzheimer's disease, provides widespread noradrenergic projections that ...
Victor Vidal, Gonzalo Farías, Carolina Delgado, Paul H. Delano, Rodrigo C. Vergara, Patricia Orellana, Tomás Ossandón, Nicolás A. Crossley, Cecilia Gonzalez‐Campo, Sharon L. Naismith, Raul Gonzalez‐Gomez, Carlos Coronel‐Oliveros, Agustín Ibáñez, Gabriel Wainstein, Robert D. Sanders, James M. Shine, Vicente Medel   +16 more
wiley   +1 more source

Cigarros eletrônicos: a novidade que virou um perigo

Debates em Psiquiatria
Os dispositivos eletrônicos para fumar (DEF), como cigarro eletrônico, vaper e pod, têm se popularizado, especialmente entre adolescentes, devido ao seu formato compacto, variedade de essências e ausência de odor desagradável.
Francielle Carvalho, Natália Marcondes Ribas, Debora Zolet Boneta, Henrique da Silva Curto Mendonça, Isabella Patricia Lando Dacroce   +4 more
doaj   +1 more source

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, Volume 67, Issue 6, Page 2796-2807, June 2026.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

Dissecting the polygenic architecture of psychopathology via singular value decomposition of eight psychiatric genome‐wide association studies and evaluation of component‐based polygenic scores

General Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Current research suggests that genetic risk for psychiatric disorders is largely due to distinct combinations of many common variants shared by different disorders. This points to the existence of latent components affecting different dimensions of psychopathology.
Fernando Facal, Ana M. Pérez‐Gutiérrez, Javier Costas   +2 more
wiley   +1 more source

Acute‐Phase Interventions After Self‐Harm for Preventing Suicide and Recurrence: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, Volume 153, Issue 6, Page 610-626, June 2026.
ABSTRACT Introduction Suicide risk is markedly elevated following presentation after self‐harm, yet the evidence base for interventions initiated in the immediate post‐presentation period has not been synthesized with specific attention to this high‐risk window. Clarifying which early interventions may reduce adverse outcomes is essential for informing
Guilherme Pimenta Roncete, Luis C. Farhat, Loren Beiram, Bianca Besteti Fernandes Damiano, Craig J. Bryan, Karina L. Ramirez, Euripedes Constantino Miguel, Rodolfo Furlan Damiano   +7 more
wiley   +1 more source

Psiquiatria e Psicanálise

Publicações ABP documentos e vídeos = ABP Publications documents and videos, 2016
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Claudio Meneghello Martin Martins, Luiz Carlos Mabilde   +1 more
openaire   +1 more source

Psychometric Properties and Longitudinal Predictors of the Columbia Suicide Severity Rating Scale (C‐SSRS) in a Brazilian Community Cohort: A 15‐Year Follow‐Up Study

Suicide and Life-Threatening Behavior, Volume 56, Issue 3, June 2026.
ABSTRACT Introduction The Columbia Suicide Severity Rating Scale (C‐SSRS) is widely used for assessing suicidal thoughts and behaviors, yet evidence on the validity of its scoring outputs in community‐based samples from low‐ and middle‐income countries remains scarce. Methods Participants included 2076 young adults (mean age 23.45, 47% female) from the
Rodolfo Furlan Damiano, Craig J. Bryan, Pedro M. Pan, Luis A. Rohde, Euripedes Constantino Miguel, Giovanni Abrahão Salum, Maurício S. Hoffmann   +6 more
wiley   +1 more source