Topical Cycling and Systemic Eligibility in Patients With Psoriasis in Japan
The Journal of Dermatology, EarlyView.ABSTRACT Topical therapy is the typical first‐line treatment for psoriasis, with the International Psoriasis Council recommending systemic therapy for patients with body surface area > 10%, high‐impact site involvement, or topical therapy failure. A recent Japanese Delphi Consensus Study proposed a definition for topical failure that considers time on ...
Akimichi Morita +6 more
wiley +1 more source
A Systemic Immune State Axis Distinguishes Psoriatic Arthritis from Psoriasis. [PDF]
Int J Mol SciLee YK, Seong HA.
europepmc +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada +9 more
wiley +1 more source
Integrating bulk RNA-seq, Mendelian randomization and single-cell RNA-seq to elucidate the roles of lactate metabolism related markers-SLC25A4 and keratinocyte in the pathogenesis of psoriasis. [PDF]
Front ImmunolWang Y, Wang X.
europepmc +1 more source
Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety
The Journal of Dermatology, EarlyView.ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley +1 more source
Forward Planning: A Staffing Framework and Ratios for Psychosocial Oncology and Supportive Care Hiring Practices as Cancer Care Models Evolve. [PDF]
Curr OncolMayer C +3 more
europepmc +1 more source
Value in the ‘valley of the shadow of death’—When the user is no longer the value arbiter
Australian Journal of Public Administration, EarlyView.Abstract The Public Service Logic (PSL) user‐centric perspective on value creation has been one of its main critiques. Scholars argue that for some real‐world applications, such as emergency services, where users cannot engage with service offerings, the PSL must consider the roles of other service actors beyond just facilitators.
Higor Leite, Stephen Osborne
wiley +1 more source
Hybrid Bacterial Colony Optimization and Particle Swarm Optimization for load balancing in fog computing. [PDF]
PLoS OneKumar A, Gupta P, Verma R.
europepmc +1 more source
Animal Conservation, EarlyView.We used a comparative study design to quantify population densities, structure, survival, cause‐specific mortality and female productivity in four West‐European hedgehog (Erinaceus europaeus) populations, and to forecast the impact of road mortality on population viability.
Lauren J. Moore +7 more
wiley +1 more source
The Role of Musculoskeletal Ultrasound in Psoriatic Arthritis: From Preclinical Detection to Treatment Monitoring. [PDF]
Curr Rheumatol RepD'Ignazio E +10 more
europepmc +1 more source