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Psoralen-Induced Phytophotodermatitis

Dermatitis, 2020
Phytophotodermatitis is a cutaneous reaction that occurs after exposure to plant-derived furocoumarins and ultraviolet A light. Psoralen is the most common phototoxic furocoumarin and is present in varying levels within many different plant species. This article focuses on the diagnosis and management of psoralen-induced phytophotodermatitis along with
Carter Ellis, Dirk M. Elston
openaire   +4 more sources

Synthesis, anti-acetylcholinesterase evaluation, molecular docking and molecular dynamics simulation of novel Psoralen derivatives.

Current Organic Synthesis, 2023
INTRODUCTION Seven new psoralen derivatives were synthesised by carbodiimide coupling to active carboxylic acid to amide formation in mild reaction conditions.
A. Hasan   +5 more
semanticscholar   +1 more source

A Metabolic Driven Bio-Responsive Hydrogel Loading Psoralen for Therapy of Rheumatoid Arthritis.

Small, 2023
Overexpressed matrix metalloproteinases, hypoxia microenvironment, and metabolic abnormality are important pathological signs of rheumatoid arthritis (RA).
Kexin Wang   +10 more
semanticscholar   +1 more source

Psoralen photochemotherapy

Journal of the American Academy of Dermatology, 1987
Psoralens and sunlight have been used by the Egyptians and Indians for hundreds of years for the treatment of vitiligo. The combination of oral psoralens and artificial ultraviolet A (PUVA) therapy was approved for the management of severe psoriasis by the Food and Drug Administration in 1982.
A K, Gupta, T F, Anderson
openaire   +2 more sources

The Safety of Psoralens

Archives of Dermatology, 1976
To the Editor.— Because of the interest in the last few years regarding the use of psoralens as a safe and effective means of repigmenting skin and acquiring a dark suntan, we believe the following case should be reported. Report of a Case.— In April 1975, a 37-year-old man was admitted to the University of California Hospital (San Francisco) for ...
George Martin   +2 more
openaire   +3 more sources

Psoralen induces hepatic toxicity through PERK and ATF6 related ER stress pathways in HepG2 cells

Toxicology Mechanisms and Methods, 2020
Psoralen has potential hepatotoxicity and has a certain promoting effect on the clinical liver injury of Psoralea corylifolia L (Fructus Psoraleae). This study investigated the underlying mechanisms of psoralen-induced hepatotoxicity in vitro.
Ying-li Yu   +6 more
semanticscholar   +1 more source

A convenient synthesis of psoralen derivatives: Psoralen, 4-methyl-psoralen and 4-phenyl-psoralen

Monatshefte f�r Chemie, 1980
AbstractZur Synthese der Titelverbindungen (I) wird die 8‐Stellung der als Ausgangsmaterialien dienenden Benzopyrane (I) mit Iod blockiert.
Chandra Prakash   +2 more
openaire   +3 more sources

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