Results 201 to 210 of about 18,448 (248)
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A convenient synthesis of psoralens

Tetrahedron, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
CHIMICHI, STEFANO   +5 more
openaire   +6 more sources

Psoralen: A Biological Important Coumarin with Emerging Applications.

Mini-Reviews in Medical Chemistry, 2020
Coumarin has a place with a class of lactones which are fundamentally comprising of a benzene ring fused to αpyrone ring, known as benzopyrones. It likewise has a conjugated framework with electron rich and good charge-transport properties.
A. Thakur   +5 more
semanticscholar   +1 more source

Comparison of psoralen-UVB and psoralen-UVA photochemotherapy in the treatment of psoriasis

Journal of the American Academy of Dermatology, 1997
PUVA treatment of psoriasis is usually given with broad-band fluorescent UVA lamps. Narrow-band UVB exposure after oral methoxsalen has been shown to achieve a greater therapeutic response in psoriasis than identical UVB exposure given without psoralen.The purpose of this study was to compare conventional PUVA with psoralen-UVB therapy in psoriasis.We ...
P.M. Farr   +4 more
openaire   +3 more sources

Psoralen and Photoactivation

Annals of Internal Medicine, 1980
Excerpt To the editor: The valuable article by Perlman and colleagues, "Photochemotherapy and Psoriatic Arthritis: A Prospective Study" (1), successfully shows that nonspondylitic psoriatic arthrit...
openaire   +3 more sources

Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts

The FASEB Journal, 2019
Bone fracture healing is a complex, dynamic process that involves various cell types, with osteoclasts and osteoblasts playing indispensable roles. In this study, we found that psoralen, the main active ingredient in Psoralea corylifolia L. fruit extract,
Tan Zhang   +7 more
semanticscholar   +1 more source

REPRODUCTIVE TOXICITY OF THE PSORALENS

Pediatric Pathology & Molecular Medicine, 2003
The psoralens are naturally occurring secondary metabolites in plants, including many fruits and vegetables. Health risks have been associated with handling or ingesting psoralen-containing plants, and with the use of synthetic psoralens in photochemotherapy of skin disorders. Our research has demonstrated that administration of the psoralens bergapten
Moussa M. Diawara, Paul J. Kulkosky
openaire   +2 more sources

Photoreactions of psoralens with lecithins

Journal of Photochemistry and Photobiology B: Biology, 1998
The formation of cyclobutane (cb) photoadducts of psoralen with a model lecithin has been shown. The adducts are formed both in ethanol solution and in micellar suspension in water. In spite of their sensitivity to various factors such as light, temperature, air, etc., they are isolated by thin-layer chromatography (TLC) and high-pressure liquid ...
Sergio Caffieri   +3 more
openaire   +3 more sources

The mechanism of Psoralen and Isopsoralen hepatotoxicity as revealed by hepatic gene expression profiling in SD rats

Basic & Clinical Pharmacology & Toxicology, 2019
The main bioactive components of Fructus psoraleae, such as psoralen and isopsoralen, are known to be hepatotoxic. However, its underlying mechanism is to be elucidated.
Lei Song   +6 more
semanticscholar   +1 more source

USE AND ABUSE OF PSORALENS

JAMA, 1960
The psoralens 1 are furocoumarins to which most people in the United States have been exposed. Celery contains psoralen. Oil of bergamot, widely used in perfumes, contains 5-methoxypsoralen. Thus, there are few persons who have not ingested psoralen and probably no adult woman who has not applied a psoralen to her skin.
openaire   +3 more sources

The Photoaddition of a Psoralen to DNA Proceeds via the Triplet State.

Journal of the American Chemical Society, 2019
Psoralens are natural compounds that serve in the light dependent treatment of certain skin diseases (PUVA therapy). They are DNA intercalators that upon photoexcitation form adducts with thymine bases.
J. Diekmann   +5 more
semanticscholar   +1 more source

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