Results 211 to 220 of about 18,448 (248)
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CRITICAL EVALUATION OF THE PSORALENS
Journal of the American Medical Association, 1959Opinions as to the usefulness of the psoralen group of drugs in treating vitiligo were obtained by questionnaire from 100 dermatologists in various parts of the world. Two dermatologists were enthusiastic about the systemic use of the psoralens, eight were vehement in their condemnation, and most considered the results poor.
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The relationship between plasma psoralen concentration and psoralen-UVA erythema
British Journal of Dermatology, 1991The plasma 8-methoxypsoralen (8-MOP) concentration was measured in 60 patients commencing psoralen photochemotherapy (PUVA). At the time of blood sampling each patient was phototested using a series of 10 exposures to UVA. The resulting erythema was measured objectively 72 h after irradiation and dose-response curves for psoralen-UVA erythema were ...
Janet McLelland +4 more
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, 1988 Furocoumarins (psoralens and isopsoralens) are natural products, occurring especially in the Umbelliferae, Rutaceae and Leguminosae (Musajo and Rodighiero 1972). They have also been isolated from microorganisms and fungi, e.g., TMP is derived from a fungus growing on diseased celery (Scheel et al. 1963).
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Psoralen photochemotherapy of psoriasis
British Journal of Dermatology, 2006The value of PUVA therapy in selected patients with severe psoriasis has been confirmed. Suppression of the disease was incomplete in those patients whose disease was unstable, with associated seborrhoeic dermatitic features. No consistent change in the proportion of epidermal cells in DNA synthesis could be demonstrated during regression of the ...
V. Manna +2 more
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ChemInform Abstract: Synthesis of Psoralens and Analogues
ChemInform, 1992AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Psoralen Phototherapy and Phototoxicity
Annals of Plastic Surgery, 1985Psoralen therapy followed by exposure to long-wave ultraviolet (UV-A) light, a combination called PUVA therapy, stimulates pigmentation of the skin. PUVA therapy is effective in the treatment of vitiligo and hypopigmented scars. Because psoralens sensitize skin to UV-A light, phototoxic reactions are frequent.
George J. Berakha, George Lefkovits
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Alkali reversal of psoralen cross-link for the targeted delivery of psoralen monoadduct lesion [PDF]
Biochemistry, 1988 Psoralen intercalates into double-stranded DNA and photoreacts mainly with thymines to form monoadducts and interstrand cross-links. We used an oligonucleotide model to demonstrate a novel mechanism: the reversal of psoralen cross-links by base-catalyzed rearrangement at 90 degrees C (BCR).
Anthony T. Yeung +2 more
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Psoralen Phototherapeutic Agents
JAMA: The Journal of the American Medical Association, 1967Photosensitizers have been used in medicine for several thousand years. In the past, the effect being sought was repigmentation of light areas in the skin. Most of the orally administered or locally applied preparations were obtained from plants that contain psoralen (furocoumarin).
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Eye protection in psoralen photochemotherapy
British Journal of Dermatology, 1981The optical performance of some commercially-available tined lenses is discussed. There is a wide variation in the UV absorbing power of sunglasses although adequate protection against solar UV-A can be achieved with some, but not all, polarizing material.
B. L. Diffey, J.B. Davey, J. A. Miller
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Kinetic study on pyrolysis of psoralen
China Journal of Chinese Materia Medica, 2012In this study, products of psoralen pyrolysis were detected using a solid pyrolysis apparatus and synchrotron radiation vacuum ultraviolet photoionization mass spectrum (SVUV-PIMS). The pyrolytic kinetics of psoralen was also studied by calculating its initial pyrolytic route in quantum chemistry.
Liao Kun +6 more
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