Results 221 to 230 of about 18,448 (248)
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The reaction of the psoralens with deoxyribonucleic acid
Quarterly Reviews of Biophysics, 1984Psoralen photochemistry is specific for nucleic acids and is better understood at the molecular level than are all other methods of chemical modification of nucleic acids. These compounds are used both forin vivostructure analysis and for photochemotherapy since they easily penetrate both cells and virus particles.
Kenneth Straub +4 more
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Chemical Research in Toxicology, 2018
Psoralen is the main active component of Psoralea corylifolia and is used as a marker to assess its quality. The effects of psoralen on animals have been well characterized. However, the molecular pathway of its toxicity is not fully understood.
Yue Zhang +8 more
semanticscholar +1 more source
Psoralen is the main active component of Psoralea corylifolia and is used as a marker to assess its quality. The effects of psoralen on animals have been well characterized. However, the molecular pathway of its toxicity is not fully understood.
Yue Zhang +8 more
semanticscholar +1 more source
Psoralen Photochemotherapy (PUVA) and Pregnancy
Archives of Dermatology, 1993Psoralen photochemotherapy (PUVA) may carry a risk of mutagenesis and teratogenesis. Using a medical birth registry and other health registries, infants born to women who had been treated with PUVA were identified. Exposure information was obtained from treating hospitals and from the license-granting agency.
Bernt Lindelöf +3 more
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Journal of Physical Chemistry B, 2018
G-quadruplex DNA has been a recent target for anticancer agents, and its binding interactions with small molecules, often used as anticancer drugs, have become an important area of research.
S. Paul, A. Samanta
semanticscholar +1 more source
G-quadruplex DNA has been a recent target for anticancer agents, and its binding interactions with small molecules, often used as anticancer drugs, have become an important area of research.
S. Paul, A. Samanta
semanticscholar +1 more source
Clinics in Dermatology, 1989
Abstract Vitiligo is an idiopathic, acquired, circumscribed hypomelanosis, which is often associated with a positive family history. It is one of the most common leukodermas affecting approximately 1–4% of the world's population. 1 Vitiligo is characterized by discrete pale white macules, few or many in number that tend to enlarge centrifugally over
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Abstract Vitiligo is an idiopathic, acquired, circumscribed hypomelanosis, which is often associated with a positive family history. It is one of the most common leukodermas affecting approximately 1–4% of the world's population. 1 Vitiligo is characterized by discrete pale white macules, few or many in number that tend to enlarge centrifugally over
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Psoralen Photobiology: Recent Advances
Photochemistry and Photobiology, 1996Clinical efficacy may arise from psoralen-induced photodamage by the induction of a panoply of biomolecules. In cellular studies with UV or photoactivatable agents, the activation of NF-kappa B, probably the most widely studied transcription factor, occurs after its release from an inhibiting factor, I kappa B.
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The Treatment of Vitiligo with Psoralen Derivatives
Archives of Dermatology, 1958During the past three years 123 patients with vitiligo have been treated with psoralen derivatives in the Dermatology Clinic, Christian Medical College Hospital, Vellore, South India. Because vitiligo is particularly disfiguring in an Indian patient, it often gives rise to severe psychological strain as well as to social stigma.
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Planta Medica, 2009