Results 81 to 90 of about 3,770 (221)
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs +6 more
wiley +1 more source
Background: Systemic oral psoralens plus UVA therapy (PUVA) is a therapeutic method used with considerable success in many different skin disorders. PUVA therapy causes some cutaneous and noncutaneous side effects and in the present research we deal with
Masoud Maleki +3 more
doaj +1 more source
Mechanistic Insights Into the Photosensitizing Properties of the Topical Retinoid Tazarotene
Light‐activated retinoids: Tazarotene and its active metabolite tazarotenic acid form long‐lived triplet excited states upon UVA irradiation, generating singlet oxygen and promoting photochemical reactions. These processes correlate with reduced fibroblast viability under light exposure, revealing potential phototoxicity and implications for combined ...
Juan A. Soler‐Orenes +5 more
wiley +1 more source
A study of comparison of PUVASOL and NBUVB in patients with vitiligo
Introduction: Vitiligo is an acquired, hypomelanotic disease, characterized by circumscribed depigmented macules. Phototherapy, which is the use of ultraviolet irradiation with or without exogenous photosensitizer is a well established treatment option ...
Vaaruni Ravishankar +4 more
doaj +1 more source
Can biowarfare agents be defeated with light? [PDF]
Biological warfare and bioterrorism is an unpleasant fact of 21st century life. Highly infectious and profoundly virulent diseases may be caused in combat personnel or in civilian populations by the appropriate dissemination of viruses, bacteria, spores,
de Sousa, Marcelo Victor Pires +6 more
core +1 more source
The eukaryotic Pso2/Snm1/Artemis proteins and their function as genomic and cellular caretakers
DNA double-strand breaks (DSBs) represent a major threat to the genomic stability of eukaryotic cells. DNA repair mechanisms such as non-homologous end joining (NHEJ) are responsible for the maintenance of eukaryotic genomes.
D. Bonatto +3 more
doaj +1 more source
Synthesis of novel psoralen analogues and their in vitro antitumor activity [PDF]
New tetracyclic benzofurocoumarin (benzopsoralen) analogues were synthesized and their inhibitory effect on the growth of tumor cell lines was evaluated. The human tumor cell lines used were MDA MB231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma)
Campos, Ana M. F. Oliveira +5 more
core +1 more source
Synthesis and characterization of psoralen analogues based on carbazoles [PDF]
Novel psoralen analogues based on carbazoles were synthesized and characterized.Fundação para a Ciência e Tecnologia (FCT) and FEDER, for National NMR ...
Campos, Ana M. F. Oliveira +2 more
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CD1a expression in psoriatic skin following treatment with propylthiouracil, an antithyroid thioureylene [PDF]
BackgroundThe antithyroid thioureylenes, propylthiouracil (PTU) and methimazole (MMI), are effective in the treatment of patients with plaque psoriasis. The mechanism of action of the drugs in psoriasis is unknown.
Alan N Elias +42 more
core +1 more source
The Risk of Cancer Associated with Immunosuppressive Therapy for Skin Diseases [PDF]
The possible carcinogenic risk of immunosuppressive therapies is an important issue in everyday clinical practise. Carcinogenesis is a slow multi step procedure, thus a long latency period is needed before cancer develops.
Väkevä, Liisa
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