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Epiplakin expression is lost in psoriatic skin lesions and is downregulated by IFN-γ in <i>ex vivo</i> skin cultures. [PDF]
Front Cell Dev BiolKühtreiber H +6 more
europepmc +1 more source
Decoding Non-Coding RNA Regulators in DITRA: From Genomic Insights to Potential Biomarkers and Therapeutic Targets. [PDF]
Genes (Basel)Spanou S +6 more
europepmc +1 more source
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Primary Health Care, 2000
Patients with psoriasis can find the psychological impact of the disease as debilitating as the physical symptoms. Helen Cloote describes the different types of psoriasis and the treatment methods available and emphasises the important role of the nurse in helping patients to come to terms with this condition.
Enno Christophers, Ulrich Mrowietz
+5 more sources
Patients with psoriasis can find the psychological impact of the disease as debilitating as the physical symptoms. Helen Cloote describes the different types of psoriasis and the treatment methods available and emphasises the important role of the nurse in helping patients to come to terms with this condition.
Enno Christophers, Ulrich Mrowietz
+5 more sources
Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review.
Journal of the American Medical Association (JAMA), 2020Importance Approximately 125 million people worldwide have psoriasis. Patients with psoriasis experience substantial morbidity and increased rates of inflammatory arthritis, cardiometabolic diseases, and mental health disorders.
A. Armstrong, C. Read
semanticscholar +1 more source
Dermatologic Clinics, 2015
The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more widely acceptable in the future ...
Menter, M Alan +1 more
openaire +6 more sources
The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more widely acceptable in the future ...
Menter, M Alan +1 more
openaire +6 more sources
Pathophysiology of psoriasis: A review
Journal of dermatology (Print), 2021Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay between multiple genetic risk foci, environmental risk factors, and excessive immunological abnormalities.
K. Yamanaka, O. Yamamoto, T. Honda
semanticscholar +1 more source
The Lancet, 1995
Psoriasis, an inherited disorder of the immune system, presents most commonly in the skin and joints but is also associated with cardiovascular, metabolic, and neuropsychiatric effects. Treatments include topical therapy for mild disease; phototherapy and oral therapy, such as retinoids and immunomodulating agents; and targeted biologic therapies that ...
openaire +3 more sources
Psoriasis, an inherited disorder of the immune system, presents most commonly in the skin and joints but is also associated with cardiovascular, metabolic, and neuropsychiatric effects. Treatments include topical therapy for mild disease; phototherapy and oral therapy, such as retinoids and immunomodulating agents; and targeted biologic therapies that ...
openaire +3 more sources
Severe psoriasis--oral therapy with a new retinoid.
Dermatologica, 1978Ro 10-9359 is a retinoic acid derivative, selected for study because of a better tolerance than retinoic acid, shown in animal experiments. Doses of 25 mg b.i.d., 25 mg t.i.d. and 50 mg b.i.d. were administered orally to 27 patients suffering from severe
T. Fredriksson, U. Pettersson
semanticscholar +1 more source