Results 71 to 80 of about 11,862,011 (403)

Real-life effectiveness of once-daily calcipotriol and betamethasone dipropionate gel vs. ointment formulations in psoriasis vulgaris: final analysis of the 52-week PRO-long study [PDF]

, 2015
Background: Topical therapies are the mainstay of treatment for psoriasis vulgaris. The fixed combination of calcipotriol (Cal) 50 mu g/g plus betamethasone 0.5 mg/g (as dipropionate; BD) is a first-line topical treatment and available as a gel or ...
Hol, CW, Lambert, Jo, Vink, J
core   +1 more source

New Treatment Addressing the Pathogenesis of Psoriasis

International Journal of Molecular Sciences, 2020
Psoriasis is an immune cell-mediated inflammatory skin disease. The interleukin (IL)23/IL17 axis plays an important role in the development of psoriasis. The effectiveness of biologic treatments such as tumor necrosis factor (TNF)α inhibitors (infliximab,
Michio Tokuyama, T. Mabuchi
semanticscholar   +1 more source

Association of Higher Levels of High‐Sensitivity C‐Reactive Protein With Future Development of Psoriatic Arthritis in Psoriasis: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder, Xianwei Li, Vinod Chandran, Cheryl F. Rosen, Richard J. Cook, Dafna D. Gladman   +5 more
wiley   +1 more source

Efficacy of ω-3 supplementation in patients with psoriasis:a meta-analysis of randomized controlled trials [PDF]

, 2019
Several studies have been conducted with the aim of investigating the effect of Omega(Ï )-3 on different psoriasis indices including Psoriasis Area and Severity Index (PASI) score, erythema, scaling, itching, area involved, and infiltration. Nevertheless,
Clark, Cain, Jafarnejad, Sadegh, Nahavandi, Mina, Taghizadeh, Mohsen   +3 more
core   +2 more sources

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]

, 2014
ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W, Azizi, Baktazh, Dhillon, Jaskaran, Fiehn, Oliver, Grapov, Dmitry, Johnson, Mary Ann, Wu, Julie   +6 more
core   +2 more sources

Progress in the treatment of nail psoriasis

Pifu-xingbing zhenliaoxue zazhi, 2023
Nail psoriasis is a clinical manifestation of psoriasis involving the nails, with prevalence of 80%~90%. Changes in nail appearance and pain can negatively impact the quality of patients′ lives.
Qian WANG, Dan HAO, Hongjie Liu, Wei LI
doaj   +1 more source

MiR-150 regulates human keratinocyte proliferation in hypoxic conditions through targeting HIF-1α and VEGFA: Implications for psoriasis treatment

PLoS ONE, 2017
Psoriasis is a common and chronic autoimmune skin disease which affects 2 to 3% of the world population. Abnormal proliferation of human keratinocytes is an important feature of psoriasis, along with local hypoxia and vascular abnormal growth.
Yongjian Li, Juan Su, Fangfang Li, Xiang Chen, Guiying Zhang   +4 more
semanticscholar   +1 more source

Direct Surface Modification of the Epidermis Using Mussel‐Inspired Polydopamine with Multiple Anti‐Biofouling Functions

Advanced Healthcare Materials, EarlyView.
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee, Hanna Lee, Jang Hwan Kim, Sungwook Park, Young Taek Oh, Hayoung Choi, Jeong‐Min Kim, Hye‐Jun Jo, Jun Hyun Park, Ho Jun Jin, Kwan Hyi Lee, Seung Ho Han, Hojun Kim, Jun Kyun Oh, Bong Hoon Kim   +14 more
wiley   +1 more source

Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology

Angewandte Chemie, EarlyView.
Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects.
Andrew G. Baker, Adrian Pui Ting Ho, Laura S. Itzhaki, Ljiljana Fruk   +3 more
wiley   +2 more sources