Results 111 to 120 of about 494,085 (317)

Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]

, 1993
In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A., Dawes, Peter T., Hothersall, T.E.   +2 more
core  

Histopathology of the gut in rheumatic diseases [PDF]

, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F., Ferrante A., Guggino G., Macaluso F., Rizzo A.   +4 more
core   +1 more source

Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force

Annals of the Rheumatic Diseases, 2017
Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in 2012, but the evidence for these recommendations was only of indirect nature. These recommendations were re-evaluated in light of new insights. Based on the results
J. Smolen, Monika Schöls, J. Braun, M. Dougados, O. FitzGerald, D. Gladman, A. Kavanaugh, R. Landewé, P. Mease, J. Sieper, T. Stamm, M. D. de Wit, D. Aletaha, X. Baraliakos, N. Betteridge, F. E. Van den Bosch, L. Coates, P. Emery, L. Gensler, L. Gossec, P. Helliwell, Merryn Jongkees, T. Kvien, R. Inman, I. McInnes, M. Maccarone, P. Machado, A. Moltó, A. Ogdie, D. Poddubnyy, C. Ritchlin, M. Rudwaleit, A. Tanew, B. Thio, D. Veale, K. de Vlam, D. M. van der Heijde   +36 more
semanticscholar   +1 more source

IMAGING OF PSORIATIC ARTHRITIS

Reumatismo, 2011
Imaging of psoriatic arthritis (PsA) is important for two reasons: the differential diagnosis from other arthritides and the assessment of structural damage that can be inhibited by the new drugs such as the anti-TNFalpha agents. Plain film radiographic findings of peripheral arthritis have been important in elaborating the concept of PsA as a separate
Salvatore D'Angelo, I. Olivieri, Enrico Scarano, Angela Padula   +3 more
openaire   +5 more sources

Efficacy of Apremilast in Refractory Genital Psoriasis: A Retrospective Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Genital pustular psoriasis is a rare and often underdiagnosed condition that can severely affect physical comfort, quality of life and psychological well‐being. It can be particularly challenging to manage, often requiring systemic therapies due to its potential unresponsiveness to conventional topical treatment.
Jonathan Krygier, Ursula Sass, Bertrand Richert   +2 more
wiley   +1 more source

Antinuclear antibodies in ankylosing spondylitis, psoriatic arthritis, and psoriasis. [PDF]

, 1979
J N Rosenberg, G.D. Johnson, E. J. Holborow   +2 more
openalex   +1 more source

The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies

Annals of the Rheumatic Diseases, 2019
Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that immune responses mediated by interleukin 17A (IL-17A) play a pivotal role in both
D. McGonagle, I. McInnes, B. Kirkham, J. Sherlock, R. Moots   +4 more
semanticscholar   +1 more source

Deucravacitinib, an Oral, Selective, Allosteric Tyrosine Kinase 2 Inhibitor, in Asian Patients With Moderate to Severe Psoriasis: Improvements in Patient‐Reported Outcomes in a Randomized Trial

The Journal of Dermatology, EarlyView.
ABSTRACT POETYK PSO‐3, a 52‐week, double‐blind, phase 3 study, evaluated the efficacy and safety of deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, in adult patients with moderate to severe plaque psoriasis in mainland China, Taiwan, and South Korea.
Jianzhong Zhang, Yangfeng Ding, Ping Wang, Linfeng Li, Weili Pan, Yan Lu, Hao Cheng, Xian Jiang, Ji‐Chen Ho, Shuping Guo, Seong Jun Seo, Linda Stein Gold, Andrew Blauvelt, Joe Zhuo, Yichen Zhong, Brandon Becker, Leona Liu, Subhashis Banerjee, Diamant Thaçi   +18 more
wiley   +1 more source

Improving Cardiovascular Outcomes in the Psoriasis Cohort. Psoriasis and Cardiovascular Disease–Patient Knowledge, Perspectives and Practice

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background and Study Aims Patient perspectives on psoriasis as a systemic disease, with its heightened risk of cardiovascular disease (CVD), are unclear. Approaches to cardiovascular risk factor screening and management vary in this cohort. This study aimed to ascertain knowledge, practice and perceptions of patients with respect to psoriasis ...
Annika Smith, Belinda Lai, Clara K. Chow, Sarah Zaman   +3 more
wiley   +1 more source

Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex. [PDF]

, 1980
Caitríona Murray, Dean L. Mann, Livia Gerber, Wilfried Barth, Stockholm Perlmann, John L. Decker, Thomas P. Nigra   +6 more
openalex   +1 more source