Results 131 to 140 of about 50,613 (304)

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Genetic epidemiology psoriatic arthritis

, 2002
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis.
Barton, Anne C.; id_orcid
core   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Psoriatic Arthritis

New England Journal of Medicine, 2017
Ciccia, F, Triolo, G, Rizzo, A.
openaire   +7 more sources

Vasculitis associated with psoriatic arthritis: a case report

Egyptian Rheumatology and Rehabilitation
Background Psoriatic arthritis is a chronic inflammatory condition associated with psoriasis, which affects joints. The coexistence of vasculitis, an inflammation of blood vessels, with psoriatic arthritis is rare, highlighting a complex interplay ...
Mehdi Jafarpour, Bita Rahbari, Bahareh Mehramuz, Sara Daneshvar   +3 more
doaj   +1 more source

Predicting Psoriatic Arthritis in Psoriasis Patients – A Swiss Registry Study

BackgroundPsoriatic arthritis (PsA) is a prevalent comorbidity among patients with psoriasis, heavily contributing to their burden of disease, usually diagnosed several years after the diagnosis of psoriasis.ObjectivesTo investigate the predictability of
Petersen, Troels C, Wu, J.J., Erik Kristensen, Lars, Boehncke, W.H., Thyssen, Jacob P., Maul, Julia-Tatjana, Wu, Jashin J., Maul, Lara Valeska, Yawalkar, Nikhil, Nielsen, M.L., Kündig, T., Navarini, A.A., Micheroli, Raphael, Schlapbach, Christoph, Petersen, Troels C., Thyssen, J.P., Thomsen, S.F., Conrad, Curdin, Egeberg, A., Egeberg, Alexander, Wu, Jashin J, Yawalkar, N., Boehncke, Wolf-Henning, Thomsen, Simon F., Micheroli, R., Thyssen, Jacob P, Cozzio, Antonio, Petersen, T.C., Erik Kristensen, L., Thomsen, Simon F, Navarini, Alexander A, Schlapbach, C., Maul, L.V., Maul, J.T., Kündig, Thomas, Conrad, C., Cozzio, A., Navarini, Alexander A., Nielsen, Mia-Louise   +38 more
core   +1 more source

The Microbiome and Psoriatic Arthritis

, 2014
Psoriatic arthritis is a chronic inflammatory joint disease, seen in combination with the chronic inflammatory skin disease psoriasis and belonging to the family of spondylarthritides (SpA).
Peppelenbosch, Maikel, Konstantinov, Sergey, Thio, Bing, H. Bing Thio, Maikel P. Peppelenbosch, Eppinga, Hester, Hester Eppinga, Sergey R. Konstantinov   +7 more
core   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Long term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis

Biologics: Targets & Therapy, 2014
Dario Kivelevitch, Bobbak Mansouri, Alan Menter Department of Dermatology, Baylor University Medical Center, Dallas, TX, USA Abstract: Psoriasis is a chronic, immune-mediated inflammatory disease affecting both the skin and joints.
Kivelevitch D, Mansouri B, Menter A
doaj