Results 111 to 120 of about 50,863 (305)

Inhibition of interleukins 17A and 17F in psoriatic arthritis [PDF]

, 2020
Psoriasis is the most common chronic inflammatory skin disease; 15–30% of patients with psoriasis have psoriatic arthritis.1 The interleukin (IL) 23 and IL17 pathway has a crucial role in pathogenesis, and inhibitors of the IL17 pathway have rewritten ...
Nash, P, Nash, Peter
core   +1 more source

Validation of International Classification of Diseases Code–Based Case Definitions of Immune Checkpoint Inhibitor–Associated Inflammatory Arthritis From Administrative Health Data

Arthritis &Rheumatology, EarlyView.
Objective Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed, Zoe Hsu, Finlay A. McAlister, William D. Leslie, Lisa M. Lix, Sasha Bernatsky, Suzanne N. Morin, Michelle M. Graham, Aurore Fifi‐Mah, Shahin Jamal, Janet Roberts, Carrie Ye   +11 more
wiley   +1 more source

Genetic epidemiology psoriatic arthritis [PDF]

, 2002
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis.
Barton, Anne C.; id_orcid
core   +1 more source

CLINICAL PRESENTATION OF PSORIATIC ARTHRITIS

Reumatismo, 2011
Psoriatic arthritis is a spondyloarthropathy, which occurs in patients with skin and/or nail psoriasis. Basing its characterization on morphological purposes, several types of arthritis have been described.
M. Atteno, R. Peluso, R. Scarpa
doaj   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

Predicting Psoriatic Arthritis in Psoriasis Patients – A Swiss Registry Study [PDF]

BackgroundPsoriatic arthritis (PsA) is a prevalent comorbidity among patients with psoriasis, heavily contributing to their burden of disease, usually diagnosed several years after the diagnosis of psoriasis.ObjectivesTo investigate the predictability of
Petersen, Troels C, Wu, J.J., Erik Kristensen, Lars, Boehncke, W.H., Thyssen, Jacob P., Maul, Julia-Tatjana, Wu, Jashin J., Maul, Lara Valeska, Yawalkar, Nikhil, Nielsen, M.L., Kündig, T., Navarini, A.A., Micheroli, Raphael, Schlapbach, Christoph, Petersen, Troels C., Thyssen, J.P., Thomsen, S.F., Conrad, Curdin, Egeberg, A., Egeberg, Alexander, Wu, Jashin J, Yawalkar, N., Boehncke, Wolf-Henning, Thomsen, Simon F., Micheroli, R., Thyssen, Jacob P, Cozzio, Antonio, Petersen, T.C., Erik Kristensen, L., Thomsen, Simon F, Navarini, Alexander A, Schlapbach, C., Maul, L.V., Maul, J.T., Kündig, Thomas, Conrad, C., Cozzio, A., Navarini, Alexander A., Nielsen, Mia-Louise   +38 more
core   +1 more source

The Microbiome and Psoriatic Arthritis [PDF]

, 2014
Psoriatic arthritis is a chronic inflammatory joint disease, seen in combination with the chronic inflammatory skin disease psoriasis and belonging to the family of spondylarthritides (SpA).
Peppelenbosch, Maikel, Konstantinov, Sergey, Thio, Bing, H. Bing Thio, Maikel P. Peppelenbosch, Eppinga, Hester, Hester Eppinga, Sergey R. Konstantinov   +7 more
core   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

IMMUNOPATHOGENESIS OF PSORIASIS AND PSORIATIC ARTHRITIS AND PHARMACOLOGICAL PERSPECTIVES

Reumatismo, 2011
Psoriasis and psoriatic arthritis are chronic inflammatory disorders resulting from a combination of genetic and environmental factors, though the precise causal agents have not yet been identified. The immune system has a major role in their development
A. Genovese, G.C. Marone, F. Ayala, S. Loffredo, G. Marone   +4 more
doaj   +1 more source