Results 141 to 150 of about 510,697 (405)

The Role of the Gut-Joint Axis in the Care of Psoriatic Arthritis: A Two-Sample Bidirectional Mendelian Randomization Study

Dermatology and Therapy
Introduction Observational studies and clinical trials have supported the association between gut microbiota and psoriatic arthritis. However, the causal link between gut microbiota and psoriatic arthritis is still unclear.
Yihong Gan, Jingqun Liu, Meng Jin, Yilin Zhang, Shuo Huang, Qing Ma, Yanzuo Wu, Li Xu, Jie Bao, Yongsheng Fan   +9 more
doaj   +1 more source

Epidemiology of psoriatic arthritis

Reumatismo, 2012
Epidemiological studies on psoriatic arthritis have long been hampered by the absence of widely accepted classification criteria. The development of the CASPAR (ClASsification criteria for Psoriatic ARthritis) criteria has recently provided the framework
C. Salvarani, N. Pipitone, M. Catanoso
doaj   +1 more source

The pathological role of Wnt5a in psoriasis and psoriatic arthritis. [PDF]

, 2019
Psoriasis (PsO) is a chronic inflammatory skin disease with both local and systemic components. PsO-associated arthritis, known as psoriatic arthritis (PsA), develops in approximately 13%-25% of PsO patients.
Li, Zhengxiao, Mauro, Theodora M, Tian, Faming   +2 more
core   +1 more source

The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies

Annals of the Rheumatic Diseases, 2019
Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that immune responses mediated by interleukin 17A (IL-17A) play a pivotal role in both
D. McGonagle, I. McInnes, B. Kirkham, J. Sherlock, R. Moots   +4 more
semanticscholar   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

BioRePortAP, an electronic clinical record coupled with a database : an example of its use in a single [PDF]

, 2010
Aims: To evaluate the efficacy and safety of the treatment of psoriatic arthritis (PsA) patients with tumor necrosis factor (TNF) antagonists in the Rheumatology Department of Hospital de Santa Maria using the BioRePortAP.
Campanilho-Marques, R., Canhao, Helena, Costa, M., Fonseca, João Eurico, Martins, F., Pereira da Silva, José A., Polido-Pereira, J., Ramos, F., Rodrigues, A., Saavedra, M. J.   +9 more
core  

Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative

Arthritis &Rheumatology, Accepted Article.
Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban, Lisa B. Rokoff, Bing Lu, Timothy E. McAlindon, Charles B. Eaton, Mary B. Roberts, Diana Mathes, Colleen Lestician, Zhijin Carrie Xu, Zhihua Tina Fan, Shawn P. O'Leary, Ida K. Haugen, Jérémie Sellam, Alice Courties, Abby F. Fleisch   +14 more
wiley   +1 more source

Remission in psoriatic arthritis: is it possible and how can it be predicted? [PDF]

, 2010
T. Saber, Chin Teck Ng, G Renard, Bernadette Lynch, Eliza Pontifex, Ceara AE Walsh, A Jordan Grier, Marian Molloy, Barry Bresnihan, Oliver FitzGerald, Ursula Fearon, Douglas J. Veale   +11 more
openalex   +1 more source

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

Nature Communications, 2019
Psoriatic arthritis (PsA) is a debilitating immune-mediated inflammatory arthritis of unknown pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary single-cell approaches to study leukocytes from PsA joints.
F. Penkava, M. D. C. Velasco-Herrera, Matthew D. Young, N. Yager, L. Nwosu, A. Pratt, Alicia Lledo Lara, C. Guzzo, A. Maroof, L. Mamanova, S. Cole, M. Efremova, D. Simone, A. Filer, Chrysothemis C. Brown, Andrew L Croxford, J. Isaacs, S. Teichmann, P. Bowness, S. Behjati, M. Hussein Al-Mossawi   +20 more
semanticscholar   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source