Persistence of biological agents over an eight-year period in rheumatoid arthritis and spondyloarthritis patients [PDF]
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
María Ángeles González-Fernández +5 more
doaj +1 more source
Treatment recommendations for psoriatic arthritis
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Gladman, D.D. +39 more
core +1 more source
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S +23 more
core +1 more source
Challenges in the Metabolomics-Based Biomarker Validation Pipeline
As end-products of the intersection between the genome and environmental influences, metabolites represent a promising approach to the discovery of novel biomarkers for diseases.
Shenghan Li +3 more
doaj +1 more source
Manifestation of palmoplantar pustulosis during or after infliximab therapy for plaque-type psoriasis : report on five cases [PDF]
Infliximab is a monoclonal antibody directed against TNF-alpha. It has been approved for use in rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriatic arthritis and plaque-type psoriasis.
Krüger, Ullrich +6 more
core +1 more source
Genome-wide association studies have recently identified a number of non-major histocompatibility complex regions associated with psoriatic arthritis.
Qing Zhao +11 more
doaj +1 more source
Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors
Psoriatic arthritis (PsA) is a chronic and painful inflammatory immune-mediated disease. It affects up to 40% of people with psoriasis and it is associated with several comorbidities such as obesity, diabetes, metabolic syndrome and hypertension.
Kuiper, JH +3 more
core +1 more source
Longitudinal profiling of the gut microbiome in patients with psoriatic arthritis and ankylosing spondylitis: a multicentre, prospective, observational study [PDF]
Background : Psoriasis is a chronic inflammatory disease of the skin affecting 2-3% ofUK population. 30% of people affected by psoriasis will develop a distinct form ofarthritis within 10 years of the skin condition onset.
Abraham, Sonya +6 more
core +1 more source
Chronic kidney disease in patients with psoriatic arthritis: a cohort study
Objectives Chronic kidney disease (CKD) is a comorbidity in psoriatic arthritis (PsA). We aimed to define the prevalence of CKD in patients with PsA, describe their long-term renal outcomes and identify risk factors for CKD development.Methods We ...
Dafna D Gladman +5 more
doaj +1 more source
ENTHESITIS AND PSORIATIC ONYCHOPATHY AS A FACTOR FOR PREDICTION OF PSORIATIC ARTHRITIS IN PSORIASIS
Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30 % of patients with psoriasis. Psoriatic arthritis affects the patient’s quality of life indicators and are more often associated with disabilities of working age than ...
Tatyana G. Sidorcika +4 more
doaj +1 more source

