Results 41 to 50 of about 93,200 (346)

Challenges in the Metabolomics-Based Biomarker Validation Pipeline

Metabolites
As end-products of the intersection between the genome and environmental influences, metabolites represent a promising approach to the discovery of novel biomarkers for diseases.
Shenghan Li, Nikita Looby, Vinod Chandran, Vathany Kulasingam   +3 more
doaj   +1 more source

Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab [PDF]

, 2013
<p>Objective To determine serum biomarker associations with clinical response to golimumab treatment in patients with psoriatic arthritis (PsA).</p> <p>Methods GO–REVEAL was a randomised, placebo-controlled study of golimumab in ...
Beutler, A., Elashoff, M., Gladman, D., Gomez-Reino, J.J., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Murphy, F.T., Papp, K., Visvanathan, S., Wagner, C.L.   +12 more
core   +1 more source

Identification of a Single Nucleotide Polymorphism in NFKBIA with Different Effects on Psoriatic Arthritis and Cutaneous Psoriasis in China

Acta Dermato-Venereologica, 2018
Genome-wide association studies have recently identified a number of non-major histocompatibility complex regions associated with psoriatic arthritis.
Qing Zhao, Yonghu Sun, Xi’an Fu, Zhenzhen Wang, Gongqi Yu, Zhenhua Yue, Yaru Wang, Huimin Zhang, Chuan Wang, Hong Liu, Qing Yang, Furen Zhang   +11 more
doaj   +1 more source

Chronic kidney disease in patients with psoriatic arthritis: a cohort study

RMD Open
Objectives Chronic kidney disease (CKD) is a comorbidity in psoriatic arthritis (PsA). We aimed to define the prevalence of CKD in patients with PsA, describe their long-term renal outcomes and identify risk factors for CKD development.Methods We ...
Dafna D Gladman, Vinod Chandran, Richard J Cook, Fadi Kharouf, Shangyi Gao, Shahad Al-Matar   +5 more
doaj   +1 more source

ENTHESITIS AND PSORIATIC ONYCHOPATHY AS A FACTOR FOR PREDICTION OF PSORIATIC ARTHRITIS IN PSORIASIS

Vestnik Dermatologii i Venerologii, 2018
Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30 % of patients with psoriasis. Psoriatic arthritis affects the patient’s quality of life indicators and are more often associated with disabilities of working age than ...
Tatyana G. Sidorcika, Viktor A. Linovs, Maya A. Radzina, Andris J. Rubins, Sylvester A. Rubins   +4 more
doaj   +1 more source

TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]

, 2017
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele, Bove, Maurizio, Cox, Maria Christina, D'Amelio, Raffaele, DI ROSA, Roberta, Lagana', Bruno, Markovic, Milica, PICCHIANTI DIAMANTI, Andrea, Pilozzi, Emanuela, Rosado, Maria Manuela, Salemi, Simonetta, Sorgi, Maria Laura   +11 more
core   +1 more source

Ustekinumab treatment and improvement of physical function and health‐related quality of life in patients with psoriatic arthritis [PDF]

, 2016
Objective: Examine ustekinumab effects on patient-reported outcomes (PROs) in PSUMMIT-1/PSUMMIT-2 patients with active psoriatic arthritis (PsA) who were methotrexate (MTX)-naïve, MTX-experienced, or anti-tumor necrosis factor (TNF)-experienced ...
Dalal, Ekelund, Feldman, Finlay, Fries, Gupta, Husted, Husted, Kavanaugh, Kimball, Koo, McInnes, Mease, Puig, Ritchlin, Schünemann, Tillett, Walsh, Ware   +18 more
core   +1 more source

The humanistic burden of atopic dermatitis in Greece: a cross-sectional study

Dermatology Reports
The purpose of this study was to evaluate the quality of life (QoL) and psychosocial burden in adult Greek patients with atopic dermatitis (AD) using validated tools and to investigate factors that influence AD’s humanistic burden.
Georgia Kourlaba, Katerina Lioliou, Garyfallia Stefanou, Soultana Koukopoulou, Eirinaios Vamvakousis, Dimitrios Ioannides   +5 more
doaj   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Incidence of Psoriatic Arthritis in Patients with Skin Psoriasis and Associated Risk Factors: A Retrospective Population-based Cohort Study in Swedish Routine Clinical Care

Acta Dermato-Venereologica, 2020
The incidence of psoriatic arthritis in patients with psoriasis is unclear; existing estimates differ by a factor of ten. Complete population-level data is needed to provide accurate estimates with high confidence.
Ingrid Lindberg, Mathias Lilja, Kirk Geale, Haijun Tian, Craig Richardson, Amie Scott, Amra Osmancevic   +6 more
doaj   +1 more source