Annals of Neurology, EarlyView.Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas +29 more
wiley +1 more source
Dialogical meanderings - evaluation framework and learnings from stakeholder involvement in the co-design of a participatory systematic review. [PDF]
Res Involv EngagemRuiz-Perez G +4 more
europepmc +1 more source
Annals of Neurology, EarlyView.Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt +82 more
wiley +1 more source
Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt
Annals of Neurology, EarlyView.As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez +5 more
wiley +1 more source
How to Prevent Suicide in Older Patients with a Neurocognitive Disorder: A Scoping Review Leading to the Development of a Clinical Guide for Healthcare Workers. [PDF]
Healthcare (Basel)Lapierre S +9 more
europepmc +1 more source
Niagara Falls City School District and Administrative and Supervisory Council of the Public Schools (2006) [PDF]
, 2006 core +1 more source
Redox‐Activated Probes Enable High‐Contrast Live Imaging of Native Postsynaptic Scaffolds
Angewandte Chemie International Edition, EarlyView.Sylives are modified fluorescent peptides for high‐contrast live imaging of inhibitory (gephyrin) and excitatory (PSD‐95) postsynaptic scaffolds in native neurons. Clean labeling requires low nanomolar probe levels, whereas uptake needs micromolar cell‐penetrating peptide (CPP).
Christiane Huhn +10 more
wiley +1 more source
Do professional experience and qualification influence knowledge about law concerning informed consent and end-of-life decisions? A quantitative online survey among German intensive care physicians. [PDF]
BMJ OpenSchumann C +8 more
europepmc +1 more source
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen +5 more
wiley +1 more source