Results 41 to 50 of about 2,043,226 (337)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Making Sense of Kleptomania: Clinical Considerations
Proceedings of Singapore Healthcare, 2010 An understanding of the historical roots, clinical features and current diagnostic criteria of kleptomania would help in a better appreciation and assessment of this condition. One of the few psychiatric conditions that is defined by an illegal activity,
Kuan Tsee Chee MBBS, MRCPsych, FAMS +3 more
doaj +1 more source
BMC Psychiatry, 2017 Background There is no consensus regarding the optimal content of the undergraduate psychiatry curriculum as well as factors contributing to young doctors choosing a career in psychiatry.
A. Appleton +3 more
doaj +1 more source
Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials
Frontiers in Psychiatry, 2020 Lysergic acid diethylamide (LSD) was studied from the 1950s to the 1970s to evaluate behavioral and personality changes, as well as remission of psychiatric symptoms in various disorders.
J. Fuentes +4 more
semanticscholar +1 more source
Integrating Ethics with Psychiatry. The case of Antoni Kępiński [PDF]
, 2016 This paper argues that in the case of mental illnesses whose somatic bases are not known or do not exist, a promising route to understand mental illness is to see it as the lack of a patient’s engagement with some moral values that are necessary for a ...
Łuków, Paweł
core +2 more sources
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
The Effect of Psychiatric Clerkship on Fifth Year Medical Students’ Attitudes Toward Psychiatry and Their Intention to Pursue Psychiatry as a Career [PDF]
Iranian Journal of Psychiatry, 2006 Objective: The purpose of this study was to examine whether attitudes toward psychiatry improved during psychiatric attachment as well as the relationship between attitudes to psychiatry and intention to pursue psychiatry as a career.
Yassaman Mottaghipour +2 more
doaj +1 more source
Psychiatry in the age of COVID‐19
World Psychiatry, 2020 World Psychiatry 19:2 June 2020 of essential mental health and psychosocial services in development and humanitarian settings during the COVID-19 pandemic.
J. Unützer, Ryan J. Kimmel, M. Snowden
semanticscholar +1 more source
Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo +14 more
wiley +1 more source
Effects of Seclusion and Restraint in Adult Psychiatry: A Systematic Review
Frontiers in Psychiatry, 2019 Background: Determining the clinical effects of coercion is a difficult challenge, raising ethical, legal, and methodological questions. Despite limited scientific evidence on effectiveness, coercive measures are frequently used, especially in psychiatry.
M. Chieze +3 more
semanticscholar +1 more source