Results 131 to 140 of about 2,267,741 (311)

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Influencing factors of leakage in patients with urostomy and research progress of nursing interventions (尿路造口患者渗漏的影响因素及护理研究进展)

open access: yes中西医结合护理
Leakage is a common complication in patients with urostomy after bladder cancer surgery, affecting patients' quality of life and psychological health. Recently, leakage in patients with urostomy has received widespread attention both at home and abroad ...
WANG Ping (王萍)   +3 more
doaj   +1 more source

Supporting Homeless People with Advanced Liver Disease Approaching the End of Life [PDF]

open access: yes, 2011
Of the thousands of people that St Mungo's supports each year, around 50 will die in their care, with advanced liver failure being the most common cause.

core  

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

open access: yesAdvanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini   +8 more
wiley   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

open access: yesAdvanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Graph analysis uncovers an opposing impact of methylphenidate on connectivity patterns within default mode network sub-divisions

open access: yesBehavioral and Brain Functions
Background The Default Mode Network (DMN) is a central neural network, with recent evidence indicating that it is composed of functionally distinct sub-networks.
Maryana Daood   +7 more
doaj   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

The person-based approach to intervention development: A scoping review of methods and applications

open access: yesDigital Health
Background The person-based approach (PBA) has emerged as a prominent methodology guiding the development of digital and hybrid health behaviour change interventions over the last decade, and there is a salient need to understand its utilization ...
Lydia Holt   +6 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Application of Psychological Nursing Care in Infants Undergoing Superficial Vein Indwelling Needle Puncturing

open access: yesHuli yanjiu, 2003
Objective: to reduce the nurse-patient quarrels, to enhance the satisfaction degree of parents for nursing skills of nurses. Method: a total of 80 infants with acute illnesses hospitalized in our department from September of 2001 to November of 2002 were
霍世英
doaj  

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