Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
The impact of generative AI use on employees' psychological distress: a moderated mediation model. [PDF]
Liu M, Li Y, Li J.
europepmc +1 more source
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
APKASS 2024 consensus statement on anterior cruciate ligament reconstruction, part Ⅲ: Return to play after anterior cruciate ligament reconstruction. [PDF]
Liang Z +23 more
europepmc +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
Mismatch Between Physical and Psychological Outcomes at Return to Sport After ACL Reconstruction and the Association With Second ACL Injury Risk: A Cohort Study. [PDF]
Piussi R +8 more
europepmc +1 more source
Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao +3 more
wiley +1 more source
Psychopathologies in post-COVID outpatients differ from a psychosomatic control sample in a cross-sectional study. [PDF]
Wintermann GB +4 more
europepmc +1 more source
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao +11 more
wiley +1 more source
Nourish to flourish: sustainable diets, sports nutrition, and psychology in college life. [PDF]
Huang J, Qi Z.
europepmc +1 more source

