Results 71 to 80 of about 6,522,528 (286)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

Análisis de los efectos de un programa de intervención psicológica en jóvenes jugadores de baloncesto [PDF]

open access: yes, 2012
This study aimed to test the effects of psychological training on young basketball players. The sample consisted in 47 male players who belong to the U-14 and U-16 teams of the same club.
Gómez Ruano, Miguel Ángel   +3 more
core   +3 more sources

Psychology and psychiatry training [PDF]

open access: yesIrish Journal of Psychological Medicine, 2005
Christopher Alan, Lewis   +5 more
openaire   +2 more sources

Scaling Up Psychological Treatments: A Countrywide Test of the Online Training of Therapists

open access: yesJournal of Medical Internet Research, 2017
Background A major barrier to the widespread dissemination of psychological treatments is the way that therapists are trained. The current method is not scalable. Objective Our objective was to conduct a proof-of-concept study of Web-centered training, a
C. Fairburn   +4 more
semanticscholar   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

open access: yesAdvanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu   +6 more
wiley   +1 more source

Dangers of Youth Sport Specialization [PDF]

open access: yes, 2018
Year-round training in a single sport is increasingly common among youth athletes. Contributing factors may include external pressures, early recruiting, pursuit of scholarships, and private leagues.Risks may include: overuse injuries, muscle imbalances,
Doveri, Marisa P., Neuffer, Jenica R.
core   +1 more source

Training health visitors in cognitive behavioural and person-centred approaches for depression in postnatal women as part of a cluster randomised trial and economic evaluation in primary care: the PoNDER trial [PDF]

open access: yes, 2011
Aim: This paper aims to describe the training preparation for health visitors who took part in the intervention arm of a cluster randomised controlled trial and economic evaluation of training for health visitors – the POstNatal Depression Economic ...
Barkham, M.   +5 more
core   +1 more source

A preliminary evaluation of the training effects of a didactic and simulation-based psychological first aid program in students and school counselors in South Korea

open access: yesPLoS ONE, 2017
The present study aimed to examine the training effects of a didactic and simulation-based psychological first aid (PFA) program. Based on the competency-based model, the study sought to examine whether the PFA training would enhance knowledge, skills ...
Jong-Sun Lee   +4 more
semanticscholar   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li   +8 more
wiley   +1 more source

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