Results 151 to 160 of about 1,377,153 (282)

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

UNIversity students' LIFEstyle behaviours and Mental health cohort (UNILIFE-M): study protocol of a multicentre, prospective cohort study. [PDF]

BMJ Open
Schuch FB, Waclawoscky A, Tornquist D, Oyeyemi AL, Sadarangani KP, Takano K, Teychenne M, Balanzá-Martínez V, O'Neil A, Romain AJ, McGrath A, Alselmi A, Andrade-Lima A, Zanetti ACG, Trompetero-González AC, Heissel A, Silva AFD, Benavides ACZ, Ruusunen A, Cristi-Montero C, Weise C, Pires DA, Silva DRP, Pelupessy DC, Dos Santos EB, Caputo EL, Critselis E, Dragioti E, Matthews E, de Jesus-Moraleida FR, Gomes FA, Bachtiar F, Silva-Junior FLE, Sallem H, Moura H, Womboh I, Grabovac I, Meyer JD, Ramos-Diaz J, Bueno-Antequera J, de Oliveira J, Deenik J, Soto-Sánchez J, van der Kaap-Deeder J, Leo Ng J, López-Gil JF, Firth J, Teixeira JA, Nikonov JR, Hoyer J, Carneiro L, Zou L, Farrer LM, Woud ML, Solmi M, Guimarães MEA, Gerber M, Reichert M, Jenkins M, Savage MJ, Hoffmann MS, Hutchesson M, Gonzalez Henao ME, Chong MJM, Morina N, Galvão-Coelho NL, Heinrichs N, Montoya-Hurtado OL, Ewah PA, Salameh P, De Boni R, Cheung RYM, Monteiro-Junior RS, White RL, Haider S, Baldew SS, Gow S, Rosenbaum S, Hallit S, Piccinin SG, Heinzel S, Torres S, Rashid T, Matias TS, Rohe T, Meireles T, Reyes-Ferrada W, Zhang Y, Frei AK, Deslandes A, Wolf S.   +90 more
europepmc   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Using natural language processing to explore differences in healthcare professionals' language on Functional Neurological Disorder: a comparative topic and sentiment analysis study. [PDF]

Front Digit Health
Mashuk MS, Lu Y, Lai LYH, Shardlow M, Saha S, Williams A, Lee A, Lloyd S, Mohanraj R, Di Basilio D.   +9 more
europepmc   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Personalised Psychological Care in Hospitals: An Organisational Model of Integrated, Patient- and Staff-Centred Services (2019-2024). [PDF]

J Pers Med
Chieffo DPR, Massaroni V, Delle Donne V, Lafuenti L, Monti L, Arcangeli V, Moriconi F, Ferrarese D, Galluzzi R, Mercuri EM, Sani G, Tortora G, Gasbarrini A.   +12 more
europepmc   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Virtual reality as a tool to enhance clinical psychology students' self-knowledge and self-awareness-a proof-of-concept study. [PDF]

Front Psychol
Stige SH, Visted E.
europepmc   +1 more source

H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety

Advanced Science, EarlyView.
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou, Renbin Dou, Rong Wu, Yunyu Xu, Ying Wang, Peng Wang, Jinfu Li, Pengcheng Lu, Yu Mao, Jieying Qian, Yunjiao Zhang, Jiqian Zhang, Shasha Zhu   +12 more
wiley   +1 more source