Results 81 to 90 of about 8,790,753 (253)

Isolation of Distinct Networks Driving Action and Cognition in Psychomotor Processes. [PDF]

open access: yes
BACKGROUND Psychomotor disturbances are observed across psychiatric disorders and often present as psychomotor slowing, agitation, disorganized behavior, or catatonia.
Shenton, Martha E   +19 more
core   +1 more source

Do preclinical seizure models predict success or failure in anti‐seizure drug development? A retrospective analysis of 89 compounds with divergent clinical outcomes for epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Anti‐seizure medication (ASM) discovery remains a major challenge despite over 30 commercially available options. One persistent obstacle for any promising candidate compound to successfully move from preclinical study to clinical approval has been the ambiguity in preclinical model selection.
Wolfgang Löscher   +1 more
wiley   +1 more source

Effects of Oxygen Prebreathing on Bubble Formation, Flow-Mediated Dilatation, and Psychomotor Performance during Trimix Dives

open access: yesSports
Introduction: This research was performed to examine the effects of air and oxygen prebreathing on bubble formation, flow-mediated dilatation, and psychomotor performance after scuba dives.
Ivana Šegrt Ribičić   +7 more
doaj   +1 more source

Investigation to determine the effects of long-term bed rest on G-tolerance and on psychomotor performance Final report [PDF]

open access: yes, 1966
Prolonged bed rest effects on gravity tolerance and psychomotor performance of ...
Henry, J. P.   +3 more
core  

Perioperative effects of melatonin and midazolam premedication on sedation, orientation, anxiety scores and psychomotor performance

open access: yes, 2004
Background and objective: To compare the perioperative effects of melatonin and midazolam given in premedication, on sedation, orientation, anxiety scores and psychomotor ...
ACIL, M   +8 more
core   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Long‐term developmental outcome in infantile epileptic spasms syndrome after high‐dose prednisolone and vigabatrin treatment

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate long‐term developmental outcomes and identify independent predictors of favorable developmental outcomes at 3 years of age in children with infantile epileptic spasms syndrome (IESS) treated with a standardized stepwise vigabatrin and high‐dose prednisolone protocol.
Soyoung Jang   +5 more
wiley   +1 more source

Action video game playing impacts occupational screening for high-stakes professionals

open access: yesCommunications Psychology
Action video game playing has been linked with enhanced cognitive and perceptual abilities measured via a variety of basic psychological lab tests. However, much less work has examined such relations in the context of measures with direct real-world ...
Aaron Cochrane   +4 more
doaj   +1 more source

Effects of Carbon Dioxide Inhalation on Psychomotor and Mental Performance during Exercise and Recovery

open access: yes, 1982
Psychomotor and mental tests involving reaction time, rotor pursuit, short-term memory for digits and letters, and reasoning ability were administered to subjects inhaling up to 5% CO2 in air and in gas mixtures containing 50% O2, The psychomotor and ...
David Kiser   +2 more
core   +1 more source

Efficacy of stiripentol, fenfluramine, and their combination on clinical outcomes in Dravet syndrome: A preliminary report

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Stiripentol and fenfluramine are approved treatments for Dravet syndrome (DS), but real‐world data comparing their effectiveness and combined use remain limited. Our study aims to explore associations between treatment with stiripentol, fenfluramine, and their combination and clinical outcomes in patients with DS.
Paolo Surdi   +7 more
wiley   +1 more source

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