Results 171 to 180 of about 397,654 (297)

Development of temperamental effortful control mediates the relationship between maturation of the prefrontal cortex and psychopathology during adolescence: A 4-year longitudinal study

, 2014
Nandita Vijayakumar, Sarah Whittle, Meg Dennison, Murat Yücel, Julian G. Simmons, Nicholas B. Allen   +5 more
openalex   +1 more source

Fledgling psychopathy or just conduct problems? Commentary on the paper: Fledgling psychopaths at midlife: Forensic features, criminal careers, and coextensive psychopathology by Matt DeLisi, Alan J. Drury & Michael J. Elbert

, 2020
Hedwig Eisenbarth, Caitlin Heesterman, Manjuparna Raychaudhuri, Kelly Shearer   +3 more
openalex   +1 more source

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

Panic Attacks as a Dimension of Psychopathology

, 2012
Neeltje M. Batelaan, Didi Rhebergen, Ron de Graaf, Jan Spijker, Aartjan T.F. Beekman, Brenda W.J.H. Penninx   +5 more
openalex   +2 more sources

Person-Centered Trajectories of Psychopathology From Early Childhood to Late Adolescence [PDF]

, 2022
Colm Healy, Ross Brannigan, Niamh Dooley, Lorna Staines, Helen Keeley, Robert Whelan, Mary Clarke, Stanley Zammit, Ian Kelleher, Mary Cannon   +9 more
openalex   +1 more source

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

Advanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi, Yeongjun Park, Jong‐eun Lee, Sunghun Kim, Bo‐yong Park, Hyunjin Park   +5 more
wiley   +1 more source

Developmental deviation in delay discounting as a transdiagnostic indicator of risk for child psychopathology [PDF]

, 2023
Jacob DeRosa, Keri S. Rosch, Stewart H. Mostofsky, Aki Nikolaidis   +3 more
openalex   +1 more source

Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP‐43‐Positive Assemblies in Motor Neuron Disease

Advanced Science, EarlyView.
Single‐molecule fluorescence microscopy is combined with proteomic profiling to fingerprint the morphology and composition of TDP‐43 protein aggregates found in post‐mortem motor neuron disease brain tissues. Aggregate fingerprints can distinguish disease from control donors and detect unexpected TDP‐43 pathology in SOD1‐MND.
Dezerae Cox, Melanie Burke, Sara Milani, Matthew A White, Fergal M Waldron, Dorothea Böken, Evgeniia Lobanova, Jemeen Sreedharan, Jenna M Gregory, David Klenerman   +9 more
wiley   +1 more source

Association of cytokines levels, psychopathology and cognition among CR-TRS patients with metabolic syndrome [PDF]

Yeqing Dong, Minghuan Zhu, Yanzhe Li, Nannan Liu, Xinxu Wang, Bing Yang, Shen Li, Zezhi Li   +7 more
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source