Results 171 to 180 of about 409,123 (298)

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

High Risk of Anxiety and Depression in Women With Different Types of Pregnancy Complications in France: A Cross-Sectional Study

Journal of Pregnancy
Jaqueline Wendland, Camila Teixeira Ribeiro, Mélina Audic, Jessica Letot, Shukrullah Ahmadi   +4 more
doaj   +1 more source

Onset of Psychopathology Among Children With Chronic Physical Illness. [PDF]

Early Interv Psychiatry
Elgie M, Yessis J, Browne DT, Ferro MA.
europepmc   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Ethnic Discrimination Moderates Genetic Influences on Adolescent Internalizing and Externalizing Psychopathology. [PDF]

Behav Genet
Su J, Trevino A, Jamil B, Lemery-Chalfant K, Elam KK, Causadias JM.   +5 more
europepmc   +1 more source

Impact of COVID-19 pandemic-related restrictive measures on overall mental and physical health and well-being, specific psychopathologies and emotional states in representative adult Greek population: Results from the largest multi-wave, online national survey in Greece (COH-FIT)

Agorastos Agorastos, Christos Christogiannis, Dimitris Mavridis, Georgios Seitidis, Katerina‐Maria Kontouli, Sofia Tsokani, Ourania Koutsiouroumpa, Konstantinos Tsamakis, Marco Solmi, Trevor Thompson, Cristoph U. Correll, Elena Dragioti, Vasilios P. Bozikas   +12 more
openalex   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk. [PDF]

J Child Psychol Psychiatry
Xie W, Wang Y, Sacks DD, Nelson CA, Bosquet Enlow M.   +4 more
europepmc   +1 more source

Vulnerability to stress and psychopathology among third year medical students

, 2015
João Gama Marques, Daniel Machado, Sílvia Ouakinin, Maria Luísa Figueira   +3 more
openalex   +1 more source

Rationale, Relevance, and Limits of Stress-Induced Psychopathology in Rodents as Models for Psychiatry Research: An Introductory Overview [PDF]

, 2020
Maria Italia, Chiara Forastieri, A Longaretti, Elena Battaglioli, Francesco Rusconi   +4 more
openalex   +1 more source